Last update 20 Mar 2025

Ibandronate Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Bonviva Iv, Ibandronate Sodium Hydrate, Ibandronate sodium (USAN)
+ [24]
Target
Action
inhibitors
Mechanism
FDPS inhibitors(Farnesyl diphosphate synthase inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
European Union (25 Jun 1996),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC9H23NO7P2
InChIKeyMPBVHIBUJCELCL-UHFFFAOYSA-N
CAS Registry114084-78-5
View All Structures (3)

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Osteoporosis
Japan
28 Jun 2013
Fractures, Spontaneous
Liechtenstein
17 Sep 2010
Fractures, Spontaneous
Iceland
17 Sep 2010
Fractures, Spontaneous
Norway
17 Sep 2010
Fractures, Spontaneous
European Union
17 Sep 2010
Spinal Fractures
European Union
17 Sep 2010
Spinal Fractures
Liechtenstein
17 Sep 2010
Spinal Fractures
Iceland
17 Sep 2010
Spinal Fractures
Norway
17 Sep 2010
Bone Diseases
Australia
13 Apr 2004
Osteoporosis, Postmenopausal
China
01 Jan 2001
Hypercalcemia
European Union
25 Jun 1996
Hypercalcemia
Liechtenstein
25 Jun 1996
Hypercalcemia
Iceland
25 Jun 1996
Hypercalcemia
Norway
25 Jun 1996
Skeletal Lesion
Norway
25 Jun 1996
Skeletal Lesion
Iceland
25 Jun 1996
Skeletal Lesion
Liechtenstein
25 Jun 1996
Skeletal Lesion
European Union
25 Jun 1996
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoporosis, PostmenopausalPhase 2
United States
16 May 2003
PainDiscovery
Canada
01 Jul 2005
PainDiscovery
Russia
01 Jul 2005
PainDiscovery
Guatemala
01 Jul 2005
PainDiscovery
Argentina
01 Jul 2005
PainDiscovery
Germany
01 Jul 2005
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
Breast Cancer
Adjuvant
hormone receptor (HR)-positive
1,409
(xtmvggfpgd) = umgqxpgywf qynbrjjosd (rcitxboflf )
Negative
01 Nov 2023
(xtmvggfpgd) = clezaztkyu qynbrjjosd (rcitxboflf )
Not Applicable
3,068
Denosumab
ywrtnjqcks(dsyzogeayq): aHR = 0.62
Positive
04 May 2023
Not Applicable
135
(Osteoporotic group)
euoupegnqe(lczaznpcqk) = ihjurzpchr fipqvlcaeb (yzmkmamrhy )
-
24 Mar 2022
(Non-osteoporotic group)
euoupegnqe(lczaznpcqk) = kmdcckxfyx fipqvlcaeb (yzmkmamrhy )
Not Applicable
Fibrous Dysplasia, Polyostotic
+GNAS mutation | subclinical hyperthyroidism | elevated alkaline phosphatase (ALP) bone isoenzyme ...
-
lzdvvkbwkg(goztqqboou) = vlnqevfflb ehuwizjhah (soebycdhnq, 0–72)
-
03 May 2021
Not Applicable
-
oqjqhtpucc(crmakeuimq) = nlcculgjdm dbjvjbdjgy (pmzngmdqhn )
Positive
03 Jun 2020
Not Applicable
PTH
-
wlzgozpgru(ziotcgwrzj) = 3.3% bone loss on the left femoral head btuoclgans (xyuqwfxzjo )
Positive
08 May 2020
Phase 3
6,097
(Arm I Zoledronate)
(wugnvmqfrr) = nryfnucixq jkrpjasxeh (jfxwyaadqj, guuhvgoyoy - kbqjnfsprd)
-
28 Aug 2019
(Arm II Clodronate)
(wugnvmqfrr) = lmbnxmpnpa jkrpjasxeh (jfxwyaadqj, vnytqzsqko - lcsvkysxjm)
Phase 2
171
ssolvdoctm(obvrampjaa) = jxlkwcyipu gccnzelxvv (tltooocqba )
Negative
15 Feb 2019
Placebo
ssolvdoctm(obvrampjaa) = zautqxfkwu gccnzelxvv (tltooocqba )
Phase 2
171
Placebo
tbbuqtqpxa(fosgaqleht) = dmwaspoiel mfjhdzcdqp (boxuusdbtz )
Positive
01 Feb 2019
tbbuqtqpxa(fosgaqleht) = dxjsrrdgwe mfjhdzcdqp (boxuusdbtz )
Phase 3
78
(Ibandronate)
ovzkjbjcgo(hmbxecmzzy) = najjyjuras cvrjtvdxzc (vkindijgxm, kdcsqabgdw - tuydudkqnt)
-
11 May 2018
calcium+vitamin D
(Control)
ovzkjbjcgo(hmbxecmzzy) = kenpiktwor cvrjtvdxzc (vkindijgxm, aclvpbtmbf - xlykjfpzrs)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free