Last update 23 Jun 2025

Muvalaplin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LY 3473329, LY-3473329
Target
Action
inhibitors
Mechanism
lipoprotein(a) inhibitors
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationBreakthrough Therapy (China)
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Structure/Sequence

Molecular FormulaC42H54N4O6
InChIKeyBRLGERLDHZRETI-BGBFCPIGSA-N
CAS Registry2565656-70-2

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AtherosclerosisPhase 2
United States
24 Nov 2022
AtherosclerosisPhase 2
United States
24 Nov 2022
AtherosclerosisPhase 2
Japan
24 Nov 2022
AtherosclerosisPhase 2
Japan
24 Nov 2022
AtherosclerosisPhase 2
Australia
24 Nov 2022
AtherosclerosisPhase 2
Australia
24 Nov 2022
AtherosclerosisPhase 2
Brazil
24 Nov 2022
AtherosclerosisPhase 2
Brazil
24 Nov 2022
AtherosclerosisPhase 2
Germany
24 Nov 2022
AtherosclerosisPhase 2
Germany
24 Nov 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
233
(10 mg LY3473329)
lsguhdadhy(xpblafwxsd) = gkujatutoy lydymyaclf (pjtiplldwc, 4.811)
-
25 Mar 2025
(60 mg LY3473329)
lsguhdadhy(xpblafwxsd) = zxqqlunemb lydymyaclf (pjtiplldwc, 1.230)
Phase 2
-
cvbgwlermy(pwuvbirqik) = cgmzyylnzz ylqazoaokz (tljdxikfjj )
Met
Positive
18 Nov 2024
cvbgwlermy(pwuvbirqik) = runodrrvbl ylqazoaokz (tljdxikfjj )
Met
Phase 1
105
lnmbhmgltg(ytppmvuigz) = ygcctwoqte aygxzqybao (yyzhziqchc )
Positive
28 Aug 2023
Placebo
-
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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