Last update 18 Jul 2026

INCB-086550

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
INCB 086550, INCB-86550
Target
Action
inhibitors
Mechanism
PDL1 inhibitors(Programmed death-ligand 1 inhibitors)
Active Indication-
Originator Organization
Active Organization-
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC41H39N7O4
InChIKeyQARLNMDDSQMINK-BVRKHOPBSA-N
CAS Registry2230911-59-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatocellular CarcinomaPhase 2
Bulgaria
02 Sep 2021
Hepatocellular CarcinomaPhase 2
Hungary
02 Sep 2021
Hepatocellular CarcinomaPhase 2
South Korea
02 Sep 2021
Hepatocellular CarcinomaPhase 2
Taiwan Province
02 Sep 2021
Hepatocellular CarcinomaPhase 2
Ukraine
02 Sep 2021
MelanomaPhase 2
Bulgaria
02 Sep 2021
MelanomaPhase 2
Hungary
02 Sep 2021
MelanomaPhase 2
South Korea
02 Sep 2021
MelanomaPhase 2
Taiwan Province
02 Sep 2021
MelanomaPhase 2
Ukraine
02 Sep 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
16
(NSCLC 400 mg BID)
kqutfrhkqg = dhetgneuoq csyollnzkc (uajznvtths, lzaxfswfus - zcoevncpes)
-
13 Mar 2025
UC
(UC 400 mg BID)
kqutfrhkqg = vlmgbrdzsg csyollnzkc (uajznvtths, azxwosdotz - fvmeaicagj)
Phase 1
138
aawyrjextg(eoyefogmcq) = wsevlxcpkk hnvwdqfnjc (snutjcjahe )
Positive
01 Nov 2022
Phase 1
79
dexgwnjstz(rsvyhzaxwh) = nyuwqutmnm jcozgudthx (ditbteybyt )
Positive
11 Nov 2021
Phase 1
IL-2 | IFN-γ | CXCL9 ...
16
INCB086550 QD 100 mg
ijwxwurmlb(lpdcwxrcsi) = jofgroyxsg ffcjbftifq (thliyojmmg )
Positive
09 Nov 2020
ijwxwurmlb(lpdcwxrcsi) = wthbnyscgp ffcjbftifq (thliyojmmg )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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