Last update 23 Jan 2025

Zirconium (89Zr) girentuximabum senvedoxamum

Overview

Basic Info

Drug Type
Radiolabeled antibody, Diagnostic radiopharmaceuticals, Monoclonal antibody
Synonyms
89Zr-DFO-GmAb, 89Zr-DFO-girentuximab, 89Zr-Girentuximab
+ [5]
Target
Mechanism
CAIX inhibitors(Carbonic anhydrase IX inhibitors), PET imaging(Positron-emission tomography enhancers)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseNDA/BLA
First Approval Date-
RegulationBreakthrough Therapy (US)
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Structure/Sequence

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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Renal Cell CarcinomaNDA/BLA
US
18 Dec 2023
Transitional Cell CarcinomaPhase 3-30 May 2023
Kidney NeoplasmsPhase 3--
Colorectal CancerPhase 2
US
06 Jun 2023
Esophageal CarcinomaPhase 2
US
06 Jun 2023
Non-Small Cell Lung CancerPhase 2
US
06 Jun 2023
Ovarian Epithelial CarcinomaPhase 2
US
06 Jun 2023
Squamous Cell Carcinoma of Head and NeckPhase 2
US
06 Jun 2023
Metastatic Triple-Negative Breast CarcinomaPhase 2
FR
21 Sep 2021
Bladder CancerPhase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
284
(beuwuitnnk) = qqvalaxmoc lqiexhwvpr (xumkbzrvvp, 80 - 90)
Met
Positive
21 Feb 2023
Phase 3
284
(zuaqktmwgm) = ekmkhamrze whfsmoupzr (uroceypopu )
Positive
06 Nov 2022
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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