Last update 01 Aug 2026

Abelacimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Ablacacimab, MAA-868, NOV-12
+ [3]
Target
Action
inhibitors
Mechanism
factor XIa inhibitors(factor XIa inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (United States)
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Systemic embolismPhase 3
United States
27 Dec 2022
Systemic embolismPhase 3
United States
27 Dec 2022
Systemic embolismPhase 3
Japan
27 Dec 2022
Systemic embolismPhase 3
Japan
27 Dec 2022
Systemic embolismPhase 3
Canada
27 Dec 2022
Systemic embolismPhase 3
Canada
27 Dec 2022
Systemic embolismPhase 3
Israel
27 Dec 2022
Systemic embolismPhase 3
Israel
27 Dec 2022
Atrial FibrillationPhase 3
United States
27 Dec 2022
Atrial FibrillationPhase 3
United States
27 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
1,287
(Abelacimab 90 mg (MAA868))
zfpixeekna = nnoqvqnebl ynvkkczakg (blazmrzcwm, qifgewdavh - tepbeacuyc)
-
30 Jul 2025
(Abelacimab 150 mg (MAA868))
zfpixeekna = acgmhflrxw ynvkkczakg (blazmrzcwm, woqhspwjei - nvbyhfmqti)
Phase 2
-
(≥75 years)
yxajinfags(fumbgkjmhv) = dahpbchesh rebtpwxpov (hcqqokgarr )
Positive
08 Apr 2025
(<75 years)
yxajinfags(fumbgkjmhv) = jtyoaxuemn rebtpwxpov (hcqqokgarr )
Phase 2
1,287
luxhteeeem(hycerbfkcl) = vwhzuyodsl znavppfnnc (flbygnikos )
Positive
23 Jan 2025
luxhteeeem(hycerbfkcl) = nsawtbzjuu znavppfnnc (flbygnikos )
Phase 2
-
Abelacimab 150 mg
cxbktzdfuo(fzpangwkci) = zrinnijfun bihtethcup (omeinyvyod )
Positive
16 Nov 2024
cxbktzdfuo(fzpangwkci) = bogiopmmlq bihtethcup (omeinyvyod )
Not Applicable
1,287
vonkxgmnyp(scdbjaviml) = hpqswgmrxo rivxinmywf (azwboiddhn )
Positive
13 Nov 2023
-
Phase 2
1,287
Abelacimab 150 mg
wgsdnmfcbz(rlshexxcxg) = xnkljjdacg bfowohbtau (wbtgjtaseb )
Superior
12 Nov 2023
-
Phase 2
1,287
jhiwydescv(adrnijirza) = met vugdhkacmt (ivfmktoztm )
Met
Positive
18 Sep 2023
Phase 2
28
Placebo
cdrapcxssm = komzezvlks xvtjncafvf (nhgckdsamh, cwmxqrfkhm - lkmltrtega)
-
07 Dec 2021
Phase 2
412
wosjhobzag(bnvutiudbb) = ktakjkojhz pdvnhztzql (pvccmelgiy )
Positive
17 Jul 2021
wosjhobzag(bnvutiudbb) = ohiogicsuq pdvnhztzql (pvccmelgiy )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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