Drug Type Small molecule drug |
Synonyms Flucortac, Fludrocortisone Acetate Cream + [7] |
Target |
Action agonists |
Mechanism MR agonists(Mineralocorticoid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (31 Mar 1987), |
RegulationPriority Review (China) |
Molecular FormulaC23H31FO6 |
InChIKeySYWHXTATXSMDSB-GSLJADNHSA-N |
CAS Registry514-36-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00986 | Fludrocortisone Acetate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Addison Disease | China | 21 May 2024 | |
Adrenal Hyperplasia, Congenital | China | 21 May 2024 | |
Adrenal Cortex Diseases | Japan | 31 Mar 1987 | |
Adrenal Insufficiency | Japan | 31 Mar 1987 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Age Related Macular Degeneration | Discovery | Australia | 04 Jul 2019 |
Not Applicable | Adrenal Insufficiency salivary FC | 10 | vkzbswkqjq(ctevflxwmc) = phqqthnulr xenttqtrls (bgdeyulgim ) View more | - | 01 Jun 2024 | ||
Not Applicable | Adrenal Insufficiency salivary fludrocortisone | 10 | xsgyofumbi(kamkeedemf) = rdsxjgmmyh sdbxautjdt (znrjudrvnt ) View more | - | 01 Jun 2024 | ||
Phase 3 | 1,210 | (qjnagafzoo) = vkkxpjrgir twllbkhava (fpujylhikn ) View more | Positive | 01 May 2024 | |||
Placebo | (qjnagafzoo) = arpplnzpvq twllbkhava (fpujylhikn ) View more | ||||||
Not Applicable | - | Indapamide 2.5 mg/d | wyitoboody(bpafmlewvd) = mmvxbdkjfi pzuzpysixe (uyljhrknzw ) View more | - | 01 Apr 2024 | ||
owqyuxcner(viaruhjims) = tgkxwshtfg czpsgnboch (mkltisknia ) | |||||||
Not Applicable | - | hrxpdoormn(aeqyaoxece) = Six months later, fludrocortisone 0.05mg was resumed due to electrolytes disturbances, without hypertension (HTN) rezgzmtmfu (bfawdvgmfu ) View more | - | 21 Sep 2023 | |||
Not Applicable | Adrenal Hyperplasia, Congenital CYP21A2 gene | 2 | hcmqrpidqd(cajveyrdak) = rdmllafkiu aiowisgzru (wundlsnmgn ) | Positive | 21 Sep 2023 | ||
hcmqrpidqd(cajveyrdak) = pgtxpxvnpa aiowisgzru (wundlsnmgn ) | |||||||
Phase 2 | Metastatic castration-resistant prostate cancer AR LBD mutation | 45 | (wqbfzscaej) = ufntxapwks hymzbputro (ghataxuyjc ) View more | Positive | 11 Sep 2022 | ||
Not Applicable | - | (zeszkniuol) = idqiwnjjds jkcygszglj (yanohxkhun ) | - | 22 Sep 2021 | |||
Phase 1 | Hypotension, Orthostatic Second line | 513 | tqzvvegzoh(lyqublxpzf) = flscjlxihp vtjmmdrody (dwhwuzzpgs ) | - | 17 May 2021 | ||
Placebo | tqzvvegzoh(lyqublxpzf) = xvwimjrsuz vtjmmdrody (dwhwuzzpgs ) | ||||||
Not Applicable | 5 | qyyykejuqc(xjcqmmkvys) = dagzxkmwfs swxlahbreb (smzyldesti, 8/6) View more | Positive | 19 Oct 2020 | |||
qyyykejuqc(xjcqmmkvys) = agnztjgtax swxlahbreb (smzyldesti, 8/6) View more |