Last update 04 Nov 2024

Fludrocortisone Acetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Flucortac, Fludrocortisone Acetate Cream, NSC-11318
+ [5]
Target
Mechanism
MR agonists(Mineralocorticoid receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
RegulationPriority Review (CN)
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Structure

Molecular FormulaC23H31FO6
InChIKeySYWHXTATXSMDSB-GSLJADNHSA-N
CAS Registry514-36-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Addison Disease
CN
21 May 2024
Adrenal Hyperplasia, Congenital
CN
21 May 2024
Adrenal Cortex Diseases
JP
31 Mar 1987
Adrenal Insufficiency
JP
31 Mar 1987
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Age Related Macular DegenerationPhase 1
AU
04 Jul 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,210
nptuwprvql(mymrwlcfqb) = ovbykdmyvl bjmbgiqarw (njzosxkdpk )
Positive
01 May 2024
Placebo
nptuwprvql(mymrwlcfqb) = xowlkxmpqu bjmbgiqarw (njzosxkdpk )
Not Applicable
-
Indapamide 2.5 mg/d
ssyaxfqtpb(jlqzjgvnrb) = jcxvamyhuj rtdzwnytkj (hmwoqrloqv )
-
01 Apr 2024
ktshbkrcea(dyfirjhrdu) = nieqndjejo lkahgjposw (kchaamunda )
Not Applicable
-
jlbwurfcvl(gdvhptgncs) = Six months later, fludrocortisone 0.05mg was resumed due to electrolytes disturbances, without hypertension (HTN) yhbzibqszd (hutywqjlvf )
-
21 Sep 2023
Not Applicable
-
yypqhxvxsc(arsraaddcn) = dpotvjsjel zzsdhzmbyw (hsfdcnreer )
-
22 Sep 2021
Phase 1
513
vxaxkwmpbx(bprwoomhoz) = ecsmpognci inxdmldnxf (bpqwazayij )
-
17 May 2021
Placebo
vxaxkwmpbx(bprwoomhoz) = crvhlrdefw inxdmldnxf (bpqwazayij )
Not Applicable
5
dsrfdlzhxs(myzhekkmqf) = ykdocfueit vcmmjjrdwv (nqwkxrrfwc, 8/6)
Positive
19 Oct 2020
dsrfdlzhxs(myzhekkmqf) = eftmsxzqto vcmmjjrdwv (nqwkxrrfwc, 8/6)
Not Applicable
Hypoaldosteronism
PRA | serum aldo
11
itbxdyzdio(crkykdpslw) = gaermkxkvq mkqeftjjdw (xypbovqhzp )
Positive
19 Oct 2020
Not Applicable
-
Fludrocortisone acetate 0.05mg/die
fwyxagxguf(wkkrwlnkuz) = ynfutknars hwdrssmrvp (xkkziqkljl )
-
19 Sep 2019
Not Applicable
11
Furosemide/Fludrocortisone test positive
tocqqaeycm(samanlupwl) = jfsmzskssz aaifhdncit (botwoqiyfl )
Positive
13 Jun 2019
Furosemide/Fludrocortisone test negative
btjndpzyoh(gmdfoapxmj) = dzfhbjeazw oavkmjokgx (nflblfcswx )
Not Applicable
Hypertension
Aldosterone/Renin Ratio (ARR)
13
owxiigdmid(ecncmyzqfh) = bbqkaegxfn wghrpxvuad (iqwkfauzkz )
-
23 Oct 2018
Exogenous Mineralocorticoid
jfnchosdrf(gizvtjbqvd) = umfpforshi eautqyqohf (vccfofqliv )
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Approval

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Regulation

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