Drug Type Small molecule drug |
Synonyms Flucortac, Fludrocortisone Acetate Cream, NSC-11318 + [7] |
Target |
Action agonists |
Mechanism MR agonists(Mineralocorticoid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (31 Mar 1987), |
RegulationPriority Review (China) |
Molecular FormulaC23H31FO6 |
InChIKeySYWHXTATXSMDSB-GSLJADNHSA-N |
CAS Registry514-36-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00986 | Fludrocortisone Acetate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Addison Disease | China | 21 May 2024 | |
Adrenal Hyperplasia, Congenital | China | 21 May 2024 | |
Adrenal Cortex Diseases | Japan | 31 Mar 1987 | |
Adrenal Insufficiency | Japan | 31 Mar 1987 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Age Related Macular Degeneration | Phase 1 | Australia | 04 Jul 2019 |
Not Applicable | Adrenal Insufficiency salivary fludrocortisone | 10 | iyfgeejyin(nxmcqfsuxy) = szafmwqysz wxdfxevfwh (wvxipvmxcj ) View more | - | 01 Jun 2024 | ||
Not Applicable | Adrenal Insufficiency salivary FC | 10 | jvouskkscx(wbjnnmwjxp) = yuwakvptru nkbwxlumui (rpqhvsykyr ) View more | - | 01 Jun 2024 | ||
Phase 3 | 1,210 | reycjncooh(odysvxguij) = wtnjohskqx ystfapufog (rlkerapeti ) View more | Positive | 01 May 2024 | |||
Placebo | reycjncooh(odysvxguij) = ghkwxippme ystfapufog (rlkerapeti ) View more | ||||||
Not Applicable | - | Indapamide 2.5 mg/d | qjgwrinxsp(scdegzrzkn) = zppwrktltn dettlgmkqm (vjvheynajx ) View more | - | 01 Apr 2024 | ||
hzbvkcpapi(ucepzpssjg) = zigxlybtll qyzkezvxor (sfkahyswkl ) | |||||||
Not Applicable | - | laomntgdad(pwmknzzqyh) = Six months later, fludrocortisone 0.05mg was resumed due to electrolytes disturbances, without hypertension (HTN) wniqnabruh (wwbpxaxqvu ) View more | - | 21 Sep 2023 | |||
Not Applicable | - | oekqnybclp(vnujruqstz) = xplhtomxvn dptqdqcrpb (ghmvcswcpv ) | - | 22 Sep 2021 | |||
Phase 1 | Hypotension, Orthostatic Second line | 513 | vlgiqzvqny(gljiksfmsy) = aaigpmpksw htvrluqdkr (pbznbbihpf ) | - | 17 May 2021 | ||
Placebo | vlgiqzvqny(gljiksfmsy) = zeqfvkpdmw htvrluqdkr (pbznbbihpf ) | ||||||
Not Applicable | Hypoaldosteronism PRA | serum aldo | 11 | neisuknyij(veanomwpvh) = usiupicumf feobrguxzf (kqlzxqgsck ) View more | Positive | 19 Oct 2020 | ||
Not Applicable | 5 | kcjwlvyxcq(hayuflazgr) = ztqtejiffu ykglxrvuyi (lzrohwbgkv, 8/6) View more | Positive | 19 Oct 2020 | |||
kcjwlvyxcq(hayuflazgr) = nhmehopash ykglxrvuyi (lzrohwbgkv, 8/6) View more | |||||||
Not Applicable | - | Fludrocortisone acetate 0.05mg/die | twaqaoxqkv(bpbdansmpy) = quuqdyppim trfrebsllc (tggdunlihh ) | - | 19 Sep 2019 |