Last update 22 Dec 2024

AST-302

Overview

Basic Info

Drug Type
DNA vaccine, Therapeutic vaccine
Synonyms
PUMVC3 DNA vaccine(University of Washington Bothell), WOKVAC, AST-302
Mechanism
HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), IGF-1R antagonists(Insulin-like growth factor I receptor antagonists), IGFBP2 inhibitors(Insulin-like growth factor binding protein IIinhibitors)
Inactive Indication
Originator Organization
Aston SCIAston SCIStartup
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPhase 2
US
30 Nov 2022
Breast Cancer 3Phase 2
US
19 Feb 2018
Residual NeoplasmPhase 2
US
19 Feb 2018
HER2 Positive Breast CancerPhase 2
US
19 Feb 2018
HER2-negative breast cancerPhase 1
US
02 Sep 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
32
WOKVAC+Sargramostim
(Treatment (WOKVAC With Sargramostim) - Dose 150 mcg + 100 mcg Sargramostim)
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-
19 Sep 2024
WOKVAC+Sargramostim
(Treatment (WOKVAC With Sargramostim) - Dose 300 mcg + 100 mcg Sargramostim)
jgfqjujojr(kwhihuwshq) = htvclzfian avyuivixfn (inbwptvxay, wfrpnlgbvn - tzkklyxbvq)
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Approval

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Regulation

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