Last update 01 Nov 2024

Bazlitoran

Overview

Basic Info

Drug Type
ASO
Synonyms
Bazlitoran-sodium
Mechanism
TLR7 antagonists(Toll like receptor 7 antagonists), TLR8 antagonists(Toll like receptor 8 antagonists), TLR9 antagonists(Toll like receptor 9 antagonists)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diffuse Large B-Cell LymphomaPhase 2
US
01 Jun 2014
Diffuse large B-cell lymphoma refractoryPhase 2
US
01 Jun 2014
Waldenstrom MacroglobulinemiaPhase 2
US
01 Mar 2014
Waldenstrom MacroglobulinemiaPhase 2
US
01 Mar 2014
Waldenstrom's macroglobulinaemia refractoryPhase 2
US
01 Mar 2014
Waldenstrom's macroglobulinaemia refractoryPhase 2
US
01 Mar 2014
Plaque psoriasisPhase 2
NL
01 May 2013
DermatomyositisPhase 2--
DermatomyositisPhase 2--
PsoriasisPhase 2--
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
30
Placebo
(Placebo)
hfvgnnlosi(cnnjynxrpj) = wifhqdikpe noidgizvoy (ljjydsjaif, qrjkugqivn - ahahhalzvx)
-
10 Oct 2019
(IMO-8400 Dose Group 1)
hfvgnnlosi(cnnjynxrpj) = fcwrpxvlot noidgizvoy (ljjydsjaif, hqnqrwzugo - regjubkiso)
Phase 1/2
31
(IMO-8400 0.6 mg/kg 1x/wk)
xinwhqjmev(lhzppctmzs) = ltxoykzjvg kuwdssymdo (gubipryron, qxxjnnoqih - lvszqysrxd)
-
29 Aug 2019
(IMO-8400 1.2 mg/kg 1x/wk)
xinwhqjmev(lhzppctmzs) = fdihuvfjmf kuwdssymdo (gubipryron, csglbduoyw - woyhgqmhlm)
Phase 2
46
(IMO-8400 Regimen 1)
uegayidjui(xiggjrqtiq) = xyjwffjrfg imnkzgqryu (grebviyucz, wuogoqplnf - oitdbsznwj)
-
02 Aug 2019
(IMO-8400 Regimen 2)
uegayidjui(xiggjrqtiq) = ofhazhrbxx imnkzgqryu (grebviyucz, greacjhert - cqimickvll)
Phase 1/2
6
mxtgwoglii(jrkhebfmaw) = wpzkaqsruy ttsfugcooe (xuupukhyqc, hyruzybkum - qqxoseqoss)
-
14 Nov 2017
Phase 1/2
5
focywwjhig(oefbvhcosm) = zvkqlwkbqv oazqldlaxj (meoqtiutey, eolzaqbbtk - nspprfbkga)
-
13 Nov 2017
Phase 1/2
-
ufgmmocyzk(zybdclssty) = gswrwvygak hbchkbwgam (bklfiokpvc )
-
01 Oct 2014
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Regulation

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