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Last update 02 Apr 2025
Recombinant staphylokinase(Supergene Co. Ltd.)
Last update 02 Apr 2025
Overview
Basic Info
Drug Type Enzyme |
Synonyms Fortelyzin, Forteplase, Gene modified staphylokinase + [3] |
Target |
Action stimulants |
Mechanism PLG stimulants(Plasminogen stimulants) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Related
7
Clinical Trials associated with Recombinant staphylokinase(Supergene Co. Ltd.)NCT06362746
Multicenter, Double-blind, Randomized, Placebo-controlled Trial of the Efficacy and Safety of a Single Bolus Administration of Non-immunogenic Recombinant Staphylokinase in Patients With Intermediate High-risk Pulmonary Embolism (FORPE-2)
NCT05372718
Multicenter, Open-label, Randomized Clinical Trial of Efficacy and Safety of the Thrombolysis With Recombinant Non-immunogenic Staphylokinase (Fortelyzin®) in Patients With ALI vs Surgery
NCT05135546
Inhaled Recombinant Non-immunogenic Staphylokinase vs Placebo in Patients With COVID-19 - FORRIF Trial
100 Clinical Results associated with Recombinant staphylokinase(Supergene Co. Ltd.)
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100 Translational Medicine associated with Recombinant staphylokinase(Supergene Co. Ltd.)
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100 Patents (Medical) associated with Recombinant staphylokinase(Supergene Co. Ltd.)
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91
Literatures (Medical) associated with Recombinant staphylokinase(Supergene Co. Ltd.)01 Feb 2025JOURNAL OF THROMBOSIS AND HAEMOSTASIS
Non-immunogenic recombinant staphylokinase versus alteplase for patients with massive pulmonary embolism: a randomized open-label, multicenter, parallel-group, non-inferiority trial, FORPE
Article
Author: Kulabukhov, Vladimir V. ; Omelchuk, Alexander M. ; Orlov, Bogdan B. ; Imad, Merai ; Soplenkova, Anna G. ; Solovyeva, Natalya V. ; Tarkhanov, Roman V. ; Konstantinov, Sergey L. ; Komarnitskaya, Mariya I. ; Kulibaba, Elena V. ; Yavelov, Igor S. ; Shogenov, Zaur S. ; Vyshlov, Eugene V. ; Leontyev, Stanislav G. ; Kirienko, Alexander I. ; Agirov, Murad M. ; Bogomazov, Ivan Yu ; Savvinova, Polina P. ; Veremeychuk, Petr V. ; Shakhnovich, Roman M. ; Bobkov, Vladimir V. ; Kashtalap, Vasily V. ; Vlasov, Petr N. ; Mullova, Irina S. ; Yasnopolskaya, Natalya V. ; Tolmacheva, Valeria Yu ; Yu Chefranova, Zhanna ; Sorokina, Anna S. ; Archakov, Alexander I. ; Furman, Nikolai V. ; Talibov, Oleg B. ; Karabach, Yuriy V. ; Ponomarev, Eduard A. ; Maksimov, Dmitry B. ; Rybin, Eugene V. ; Teterina, Marina A. ; Kutsenko, Vladimir A. ; Ivanov, Sergey V. ; Lykov, Yury A. ; Koledinskii, Anton G. ; Pribylov, Sergey A. ; Panina, Elena S. ; Libov, Igor A. ; Komissarova, Ekaterina V. ; Tereschenko, Sergey N. ; Pecherina, Tamara B. ; Erlikh, Alexey D. ; Zolkin, Vladimir N. ; Cherepanova, Natalya A. ; Ludnev, Leonid O. ; Kurtasov, Dmitry S. ; Linev, Kirill A. ; Yu Vasilieva, Elena ; Markin, Sergey S. ; Igoshin, Alexander S. ; Oleynikov, Valentin E. ; Klein, Harry V. ; Makukhin, Valery V. ; Semenov, Michail P. ; Avdeeva, Irina A. ; Duplyakov, Dmitry V. ; Stryabkova, Galina I. ; Semenov, Andrey M. ; Ivlev, Oleg E. ; Beregovykh, Valery V. ; Vyazova, Natalia L. ; Ivanov, Vladimir S. ; Yarovaya, Elena B. ; Rabinovich, Robert M. ; Komarova, Anna G.
01 Jan 2023Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
[Multicenter experience of using Fortelyzin during staged reperfusion therapy of acute ischemic stroke in anterior circulation].
Article
Author: Mingazetdinov, M A ; Telyatnik, Yu A ; Mukhamadieva, Y S ; Yusupov, R I ; Demin, T V ; Zagidullin, B I ; Timchenko, L V ; Sinutin, V N ; Volodyukhin, M Yu ; Khasanova, D R ; Podshivalov, I A
01 Jan 2022Computational and structural biotechnology journalQ3 · BIOLOGY
Computer-aided engineering of staphylokinase toward enhanced affinity and selectivity for plasmin
Q3 · BIOLOGY
ArticleOA
Author: Toul, Martin ; Mikulik, Robert ; Vitecek, Jan ; Thalerova, Sandra ; Prokop, Zbynek ; Fleishman, Sarel J ; Damborsky, Jiri ; Peskova, Michaela ; Kittova, Patricia ; Nikitin, Dmitri ; Mican, Jan ; Bednar, David ; Marek, Martin
100 Deals associated with Recombinant staphylokinase(Supergene Co. Ltd.)
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Acute Lung Injury | Phase 3 | Russia | 26 Dec 2022 | |
| Limb ischemia | Phase 3 | Russia | 26 Dec 2022 | |
| COVID-19 | Phase 3 | Russia | 27 Dec 2021 | |
| Pulmonary Embolism | Phase 3 | Russia | 15 Dec 2020 | |
| Acute Ischemic Stroke | Phase 3 | Russia | 18 Mar 2017 | |
| Androgen-Insensitivity Syndrome | Phase 3 | Russia | 18 Mar 2017 | |
| ST Elevation Myocardial Infarction | Phase 3 | Russia | 16 May 2014 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 3 | 310 | (Recombinant Nonimmunogenic Staphylokinase) | nqhoytyfjq = txlphapjbg ykpcyuwple (xwhrzcerzj, mpyvolzkry - jspqoqpkko) View more | - | 02 Apr 2025 | ||
(Alteplase) | nqhoytyfjq = wrkvnwmsqw ykpcyuwple (xwhrzcerzj, bfnwwvusta - zermqzsebn) View more | ||||||
Phase 3 | 382 | (Recombinant Staphylokinase) | yewuaspvgn = wuovekjluz xqmbitrifc (tbtekvwjau, ijzdrqiabc - ggrznlqsbe) View more | - | 25 Mar 2025 | ||
(Tenecteplase) | yewuaspvgn = rkplxjzubp xqmbitrifc (tbtekvwjau, kzakbopive - ldqlwjhjvx) View more | ||||||
Phase 3 | 336 | Non-immunogenic staphylokinase | qkzepgydwo(zmbliefzte) = fadqxxpulx jousfdzujk (ornoygklui ) View more | Positive | 01 Sep 2021 | ||
qkzepgydwo(zmbliefzte) = tyrwauyyna jousfdzujk (ornoygklui ) View more |
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