Last update 27 Feb 2026

ADU-1604

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms-
Target
CTLA4
Action
inhibitors
Mechanism
CTLA4 inhibitors(Cytotoxic T-Lymphocyte-Associated Antigen 4 inhibitors)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Metastatic melanoma
Inactive Indication-
Originator Organization
Aduro BioTech, Inc.Aduro BioTech, Inc.
Active Organization
Sairopa B.V.Sairopa B.V.
Inactive Organization
Aduro BioTech, Inc.Aduro BioTech, Inc.
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with ADU-1604
CTIS2024-511949-19-00
/ CompletedPhase 1
An Open-Label, Multicenter, Phase 1 Study Evaluating the Safety and Pharmacokinetics of ADU-1604 in Adults with Advanced Melanoma
NCT03674502
/ TerminatedPhase 1
A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of ADU-1604, an Anti-CTLA-4 Antibody, in Adults With Metastatic Melanoma
100 Clinical Results associated with ADU-1604
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100 Translational Medicine associated with ADU-1604
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100 Patents (Medical) associated with ADU-1604
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100 Deals associated with ADU-1604
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic melanomaPhase 1
France
Aduro BioTech, Inc.Aduro BioTech, Inc.
08 Nov 2018
Metastatic melanomaPhase 1
Spain
Aduro BioTech, Inc.Aduro BioTech, Inc.
08 Nov 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
SITC2023
Phase 1
Refractory Melanoma
ICOS | Ki-67 | ALC
-
mmucuzrdfa(tnxjokmrgg) = dose-dependent increase of ALC and CD4+ and CD8+ T cells ficnwshtxd (qrinalurrc )
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-
02 Nov 2023
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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