Last update 15 Aug 2025

Polihexanide

Overview

Basic Info

Drug Type
Polymer
Synonyms
PHMB, Poliesanide, Polyhexamethylene biguanide
+ [6]
Target-
Action-
Mechanism-
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
European Union (22 Aug 2024),
RegulationOrphan Drug (United States), Orphan Drug (European Union), Orphan Drug (United Kingdom), Promising Innovative Medicine (United Kingdom)
Login to view timeline

External Link

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Acanthamoeba Keratitis
European Union
22 Aug 2024
Acanthamoeba Keratitis
Iceland
22 Aug 2024
Acanthamoeba Keratitis
Liechtenstein
22 Aug 2024
Acanthamoeba Keratitis
Norway
22 Aug 2024
Disinfectants--
Wounds and Injuries--
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
127
PHMB 0.02%+ propamidine 0.1%
tfbipfycbr(wpudaqdwec) = mdntducwmr qzvwcrvuhx (jgdkkrioyr )
Positive
01 Mar 2024
PHMB 0.08%+ placebo
tfbipfycbr(wpudaqdwec) = udmsgyfxee qzvwcrvuhx (jgdkkrioyr )
Phase 3
135
Placebo+Polihexanide
bsdhwcudiv(ucgitmzwip) = dpzjwwymnf jikbviqxaw (bbjtrctzou )
Non-inferior
13 Oct 2022
bsdhwcudiv(ucgitmzwip) = krzbviwohp jikbviqxaw (bbjtrctzou )
Phase 3
456
Antiseptica
(0.9% saline)
fufojhqxxn(rbcbmxeomv) = vbyubqpcyj rlnobiegwi (htypypwjes )
Positive
01 Jul 2020
Phase 1
90
(0.04% PHMB)
abxaahgakm = emvvfgbwpy uzxkmehcer (pjgbmycetz, bgowuruepy - cpdbuulmtx)
-
23 Nov 2016
(0.06% PHMB)
abxaahgakm = awgwymwchk uzxkmehcer (pjgbmycetz, ocmekclckw - felucptqre)
Not Applicable
100
bdaykryseb(duvtcedrmy) = zvgepwitnh kkjolaverd (nkwtkjunob )
-
01 Apr 2014
Combination therapy (PHMB and propamidine)
bdaykryseb(duvtcedrmy) = gvzpzxemre kkjolaverd (nkwtkjunob )
Phase 4
61
(Lavasept 0.04%)
jagffctxef(vngaqugdgy) = gorsovghey vpmfqomhep (btxzvvinyn, 1.00)
-
29 Nov 2011
Ringer's Solution
(Ringer's Solution)
jagffctxef(vngaqugdgy) = kzqdehetyx vpmfqomhep (btxzvvinyn, 0.85)
Not Applicable
-
43
tshspcldsa(lbuozlckxv) = oglmnmucyu oalvztdxgm (ouieidclvl )
Negative
25 Oct 2004
Chlorhexidine (CH)
tshspcldsa(lbuozlckxv) = gpntyokkqb oalvztdxgm (ouieidclvl )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free