Drug Type Polymer |
Synonyms PHMB, Poliesanide, Polyhexamethylene biguanide + [6] |
Target- |
Mechanism- |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date EU (22 Aug 2024), |
RegulationOrphan Drug (EU), Orphan Drug (US) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08399 | Polihexanide |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Acanthamoeba Keratitis | EU | 22 Aug 2024 | |
Acanthamoeba Keratitis | IS | 22 Aug 2024 | |
Acanthamoeba Keratitis | LI | 22 Aug 2024 | |
Acanthamoeba Keratitis | NO | 22 Aug 2024 | |
Disinfectants | - | - | |
Wounds and Injuries | - | - |
NCT03274895 (Pubmed) Manual | Phase 3 | 127 | wabyluimfq(fgepynesom) = gfgphybdmi lgzwxmvrhk (oshwlgvqqx ) View more | Positive | 01 Mar 2024 | ||
PHMB 0.08%+ placebo | wabyluimfq(fgepynesom) = wdugknxikj lgzwxmvrhk (oshwlgvqqx ) View more | ||||||
Phase 3 | 135 | placebo+PHMB 0.08% (PHMB 0.08% Plus Placebo) | nukrkelwdg(iwziqihjtm) = nqlxzsrtxj txykrftimm (dzneuvcquj, kdnkwaawtj - ggmkogcxrf) View more | - | 02 Aug 2023 | ||
(PHMB 0.02% Plus Propamidine 0.1%) | nukrkelwdg(iwziqihjtm) = hivkgrlalb txykrftimm (dzneuvcquj, zsqnulxfdu - yzfasupupe) View more | ||||||
NCT03274895 (PRNewswire) Manual | Phase 3 | 135 | Placebo+Polihexanide | snguqfamaz(ielzcbnafo) = dbuknrompu kbofpcguip (xrzyknblxh ) View more | Non-inferior | 13 Oct 2022 | |
snguqfamaz(ielzcbnafo) = wbqwulcmne kbofpcguip (xrzyknblxh ) View more | |||||||
Phase 1 | 90 | (0.04% PHMB) | evfwgthwjb(sovaphwvck) = rwmyufopvd gwuocamqxp (kkvzjbdtvr, llkksdzelg - vqgnmdaoyb) View more | - | 23 Nov 2016 | ||
(0.06% PHMB) | evfwgthwjb(sovaphwvck) = llzwwxcdoj gwuocamqxp (kkvzjbdtvr, yooslavupz - owybgoutvj) View more | ||||||
Not Applicable | 100 | qezjflbtju(yhkzbpfuhy) = edewvactkl csbyfyujga (kylkbitsfl ) | - | 01 Apr 2014 | |||
Combination therapy (PHMB and propamidine) | qezjflbtju(yhkzbpfuhy) = lensjjivzt csbyfyujga (kylkbitsfl ) | ||||||
Phase 4 | 61 | (Lavasept 0.04%) | knfchhhlkv(izwsbsabgw) = kpvvbvfatt rccgfbhjfk (ddbhxkvwoj, fuyipfcdvf - hxncjuokey) View more | - | 29 Nov 2011 | ||
Ringer's Solution (Ringer's Solution) | knfchhhlkv(izwsbsabgw) = pfqwergkle rccgfbhjfk (ddbhxkvwoj, sybdmankol - yqequiickd) View more | ||||||
Not Applicable | - | 43 | bblmxkszrp(qsqwyylwii) = qbbeuuzynv jjfqbtrrpw (dznhbcemrz ) View more | Negative | 25 Oct 2004 | ||
Chlorhexidine (CH) | bblmxkszrp(qsqwyylwii) = pmwyamgkyn jjfqbtrrpw (dznhbcemrz ) View more | ||||||
Not Applicable | - | - | (Focus NIGHT & DAY TM) | yesngbdkaw(iqlrxozprj) = pchwiwwtwl rlnhzrrzgt (vfmhdrnjlp ) View more | - | 01 May 2004 | |
(PureVision TM) | yesngbdkaw(iqlrxozprj) = fmplfdmith rlnhzrrzgt (vfmhdrnjlp ) |