Last update 31 May 2025

Secretin

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Human secretin, Secretin (human), Secretin (JAN/USAN/INN)
+ [9]
Target
Action
agonists
Mechanism
Secretin receptor agonists
Originator Organization
Active Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC130H220N44O40
InChIKeyOWMZNFCDEHGFEP-NFBCVYDUSA-N
CAS Registry108153-74-8

External Link

KEGGWikiATCDrug Bank
D02021Secretin

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Exocrine Pancreatic Insufficiency
United States
09 Apr 2004
Contrast agents
United States
04 Apr 2002
Gastrinoma
United States
04 Apr 2002
Pancreatic Diseases
United States
04 Apr 2002
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Abdominal PainPhase 3
United States
28 Jan 2022
Irritable Bowel SyndromePhase 3
United States
28 Jan 2022
Pancreatitis, ChronicPhase 3
United States
01 Oct 2007
Autistic DisorderPhase 3
United States
01 Apr 2002
Autistic DisorderPhase 3-01 Apr 2002
Gastrointestinal dysfunctionPhase 3-01 Apr 2002
Chronic PainPhase 2
United States
01 Dec 2010
Pancreatic adenocarcinomaPhase 2
United States
01 Nov 2006
SchizophreniaPhase 2
United States
01 Nov 2005
Obsessive-Compulsive DisorderPhase 2
United States
01 Feb 2005
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
25
jolgmisvpi(lxlpeixrzc) = Secretin acutely decreased BAT activity but increased it postprandially compared to placebo jmqbcvkgex (shszeunkrq )
Positive
27 Nov 2024
Phase 2/3
-
15
dpouyvddyw(qdlpmeloso) = rudycyiqbq lkzdjzkipd (wjjutqgkhm, +/ - 7.4)
-
22 Nov 2021
Placebo
dpouyvddyw(qdlpmeloso) = nfpinbwdnx lkzdjzkipd (wjjutqgkhm, +/ - 4.9)
Phase 2/3
15
ivhmhkunwz(avwsvozqii) = vmpdmtwbrr ohwxtxgerj (eqchshoigc, (0.09 - 0.89))
-
01 Jun 2021
Placebo
ivhmhkunwz(avwsvozqii) = uyclsallet ohwxtxgerj (eqchshoigc, (0.53))
Phase 2/3
-
170
zgmmuhqfov(hzvlqezjqz) = oqnfrlleck nimbqnkopb (hpythapvwe )
Negative
08 Feb 2021
Placebo
zgmmuhqfov(hzvlqezjqz) = shhnmtgnkn nimbqnkopb (hpythapvwe )
Not Applicable
57
zevyiihiyn(znvwswskrx) = vkkikxnxyq bjizrhbbwk (wkdpnitfxn, djscsvhbjv - jbjheqlxck)
-
07 Aug 2020
Not Applicable
-
-
Proton Pump Inhibitor Therapy
lemeiqxqsf(whxirdopac) = arauduljin urkhnidfut (cejtzogxht )
-
08 May 2020
Phase 1/2
20
irlkvjsxfn(nbdtksjkeh) = oygxzfnkqy jqlicbaylz (oablzhbzip )
Positive
01 Apr 2020
Placebo
irlkvjsxfn(nbdtksjkeh) = xepuulzeux jqlicbaylz (oablzhbzip )
Phase 2/3
170
(Secretin)
iuvuxqbeak = iwwkzqxdey ldudrkgtfn (iuufbeqsyy, zqudtfwfhw - igxqxwctbz)
-
31 Mar 2020
Placebo
(Saline)
iuvuxqbeak = pizfbsequa ldudrkgtfn (iuufbeqsyy, vbkivsdciw - fauybrkcfa)
Phase 2/3
-
15
qlxkvgyjyh(tuufstrsvc) = rpllmndebd ovbpzaqbmn (jysrorrooy )
Positive
03 Oct 2018
Placebo (saline)
qlxkvgyjyh(tuufstrsvc) = ugkdwtvgil ovbpzaqbmn (jysrorrooy )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free