Drug Type Universal CAR-T |
Synonyms CD7 targeting chimeric antigen receptor T cell therapy Yake Biotechnology |
Target |
Mechanism CD7 inhibitors(T-cell antigen CD7 inhibitors), Gene transference, T lymphocyte replacements |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
acute leukemia | Phase 2 | CN | 18 Feb 2024 | |
CD7 positive Hematologic Neoplasms | Phase 2 | CN | 30 Apr 2023 | |
CD7 positive Hematologic Neoplasms | Phase 2 | CN | 30 Apr 2023 | |
Crohn Disease | Phase 1 | CN | 28 Feb 2022 | |
Crohn Disease | Phase 1 | CN | 28 Feb 2022 | |
Acute Myeloid Leukemia | Phase 1 | CN | 01 Apr 2021 | |
CD7 Positive Neoplasms | Phase 1 | CN | 01 Apr 2021 | |
CD7 Positive T-Cell Leukemia | Phase 1 | CN | 01 Apr 2021 | |
T-Cell Lymphoma | Phase 1 | CN | 01 Apr 2021 | |
T-Cell Prolymphocytic Leukemia | Preclinical | CN | 15 Apr 2021 |
NCT04599556 (EBMT2023) Manual | Phase 1/2 | 9 | (btwpcflksz) = Adverse events including cytokine release syndrome grade 1-2 occurred in all patients (n=9) and cytopenia grade 3-4 in 100% (n=9), neurotoxicity grade 1-2 in 11.1% (n=1), and viral activation grade 1-2 in 22.2% (n=2) esdlarcdqv (jkyqsafcqr ) | Positive | 26 Apr 2023 | ||
NCT04823091 (EHA2022) Manual | Phase 1 | 10 | (wrkbrkywjm) = cbnazykqsd lroyaewzbw (bapacchqnj ) View more | Positive | 12 May 2022 |