Last update 01 Nov 2024

Anti-CD7 CAR-T cell therapy (Yake Biotechnology)

Overview

Basic Info

Drug Type
Universal CAR-T
Synonyms
CD7 targeting chimeric antigen receptor T cell therapy Yake Biotechnology
Target
Mechanism
CD7 inhibitors(T-cell antigen CD7 inhibitors), Gene transference, T lymphocyte replacements
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
acute leukemiaPhase 2
CN
18 Feb 2024
CD7 positive Hematologic NeoplasmsPhase 2
CN
30 Apr 2023
CD7 positive Hematologic NeoplasmsPhase 2
CN
30 Apr 2023
Crohn DiseasePhase 1
CN
28 Feb 2022
Crohn DiseasePhase 1
CN
28 Feb 2022
Acute Myeloid LeukemiaPhase 1
CN
01 Apr 2021
CD7 Positive NeoplasmsPhase 1
CN
01 Apr 2021
CD7 Positive T-Cell LeukemiaPhase 1
CN
01 Apr 2021
T-Cell LymphomaPhase 1
CN
01 Apr 2021
T-Cell Prolymphocytic LeukemiaPreclinical
CN
15 Apr 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
9
(btwpcflksz) = Adverse events including cytokine release syndrome grade 1-2 occurred in all patients (n=9) and cytopenia grade 3-4 in 100% (n=9), neurotoxicity grade 1-2 in 11.1% (n=1), and viral activation grade 1-2 in 22.2% (n=2) esdlarcdqv (jkyqsafcqr )
Positive
26 Apr 2023
Phase 1
10
(wrkbrkywjm) = cbnazykqsd lroyaewzbw (bapacchqnj )
Positive
12 May 2022
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Approval

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Regulation

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