Last update 05 Dec 2024
RC-148
Last update 05 Dec 2024
Overview
Basic Info
Drug Type Bispecific antibody |
Synonyms RC 148, RC148 |
Target |
Mechanism PD-1 modulators(Programmed cell death protein 1 modulators), VEGF modulators(Vascular endothelial growth factor modulators) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Gene Sequence
Sequence Code 160581189
Related
4
Clinical Trials associated with RC-148A Randomized, Open-label, Controlled, Multicenter Phase II Study to Evaluate the Efficacy and Safety of Disitamab Vedotin Combined With RC148 Versus Albumin-bound Paclitaxone Alone or in Combination With Toripalimab in Subjects With HR-negative, HER2-low Expressing Unresectable Locally Advanced or Metastatic Breast Cancer
Safety, Tolerability, Pharmacokinetics, and Efficacy of RC148 in Patients With Locally Advanced Unresectable or Metastatic Solid Tumors: an Open-Label, Multicenter, Phase I Trial
评价RC148注射液单药及联合方案治疗局部晚期不可切除或转移性恶性实体肿瘤患者的疗效和安全性的多中心Ⅰ/Ⅱ期临床研究
[Translation] A multicenter phase I/II clinical study to evaluate the efficacy and safety of RC148 injection alone and in combination with other drugs in the treatment of patients with locally advanced unresectable or metastatic malignant solid tumors
100 Clinical Results associated with RC-148
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100 Translational Medicine associated with RC-148
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100 Patents (Medical) associated with RC-148
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100 Deals associated with RC-148
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| HR-negative/HER2-low Breast Carcinoma | Phase 2 | CN | 01 Nov 2024 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | CN | 07 Sep 2023 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | CN | 14 Sep 2023 | |
| CLDN18.2 Positive Advanced Malignant Solid Neoplasm | IND Approval | CN | 25 Jul 2024 | |
| HER2-Low Breast Carcinoma | IND Approval | CN | 23 Jul 2024 |
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