Drug Type Monoclonal antibody |
Synonyms Amatuximab (USAN), Anti-mesothelin monoclonal antibody + [1] |
Target |
Action inhibitors |
Mechanism MSLN inhibitors(Mesothelin inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationOrphan Drug (European Union) |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09767 | Amatuximab | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Mesothelioma | Phase 2 | - | - | |
Pancreatic Cancer | Phase 2 | - | - | |
Malignant Pleural Mesothelioma | Preclinical | Netherlands | 31 Dec 2008 | |
Malignant Pleural Mesothelioma | Preclinical | Canada | 31 Dec 2008 | |
Malignant Pleural Mesothelioma | Preclinical | Spain | 31 Dec 2008 | |
Pancreatic carcinoma non-resectable | Preclinical | United States | 01 Dec 2007 | |
Pancreatic carcinoma non-resectable | Preclinical | Germany | 01 Dec 2007 | |
Pancreatic carcinoma non-resectable | Preclinical | Belgium | 01 Dec 2007 | |
Pancreatic carcinoma non-resectable | Preclinical | Spain | 01 Dec 2007 | |
Pancreatic carcinoma non-resectable | Preclinical | Canada | 01 Dec 2007 |
Phase 2 | 89 | (All Participants) | vzqljjexcp(grnirajzhh) = dlctxhyagq gcznvhowts (uyehrpjqnc, spcqpfrqyw - bncqwrsmhb) View more | - | 22 Sep 2022 | ||
(Amatuximab/Pemetrexed/Cisplatin) | bfrngbnvrz(uipdnzqifs) = psxgqelxgg nagxfzfxoo (hkloznwijp, uzfiaxjyvc - xwhahzpzea) View more | ||||||
Phase 2 | 124 | (Combination Treatment Phase:Amatuximab + Pemetrexed +Cisplatin) | (qalbfruekw) = cmtqtcispg qoihxemvjw (kowneovpff, ugbnwwkbcu - qgahbyvdmn) View more | - | 17 Mar 2020 | ||
(Combination Treatment Phase: Placebo + Pemetrexed + Cisplatin) | (qalbfruekw) = qyecruqmnq qoihxemvjw (kowneovpff, hpqnquldey - nqaqhebqpw) View more | ||||||
Phase 2 | 560 | Amatuximab + P/C | (wyxbpwhngq) = tdoujgjyms bmsxkjhqtw (exahugvjsd ) | - | 20 May 2016 | ||
Phase 1 | 17 | (vdlakdhlax) = pxszmmcrjc susaoiiwbd (xbiafcwynx ) View more | - | 01 Apr 2015 | |||
Not Applicable | 89 | (nnyvxpslab) = tlooaetkqx nmpagqyrvs (okkyobjozt ) View more | - | 29 Oct 2013 | |||
Phase 2 | 89 | (qojpicubpp) = yauykwggyi qnchrvkvhp (trddyhslzp ) View more | - | 20 May 2012 | |||
Phase 2 | 155 | (MORAb-009 Plus Gemcitabine ('MORAb-009')) | (ugqwdfsehb) = yrlmvzzzpn lnnznoesti (znwefselvv, jzkoxbirdd - pcnwsugdpw) View more | - | 27 Mar 2012 | ||
Placebo+Gemcitabine (Placebo Plus Gemcitabine ('Placebo')) | (ugqwdfsehb) = ioomwnsgaj lnnznoesti (znwefselvv, smisrrjqat - sqfntsipld) View more |