Drug Type Small molecule drug |
Synonyms Ct-053 free base, Ct-053-ptsa free base, Ct053ptsa free base + [4] |
Action inhibitors, antagonists |
Mechanism AXL inhibitors(AXL receptor tyrosine kinase inhibitors), FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors), MerTK inhibitors(Tyrosine-protein kinase Mer inhibitors) |
Therapeutic Areas |
Active Indication |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
Molecular FormulaC38H37FN4O8S |
InChIKeyNAUYISNCVNUUDK-UHFFFAOYSA-N |
CAS Registry1394820-77-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Non-Small Cell Lung Cancer | Phase 2 | - | 27 Nov 2022 | |
Advanced Hepatocellular Carcinoma | Phase 2 | China | 07 Jun 2021 | |
Metastatic Renal Cell Carcinoma | Phase 2 | China | 25 Jun 2018 | |
Renal Cell Carcinoma | Phase 2 | China | 25 Jun 2018 | |
EGFR T790M Mutation Positive Non-Small Cell Lung Carcinoma | Phase 2 | China | 01 Nov 2016 | |
Kidney Neoplasms | Phase 1 | China | 30 Jan 2022 | |
Leukemia | Phase 1 | China | 30 Jan 2022 | |
FLT3 positive Acute Myeloid Leukemia | Phase 1 | China | 13 Nov 2017 | |
Relapsing acute myeloid leukemia | Phase 1 | China | 13 Nov 2017 | |
Intestinal Neoplasms | Phase 1 | China | 08 Apr 2014 |
Phase 1 | Non-Small Cell Lung Cancer T790M Negative | 86 | banzyvubjg(swaaowtisx) = epsejyxunr eofvubqlfg (qntcgfxcjf ) View more | Positive | 29 May 2020 |