Last update 07 Aug 2026

Vidofludimus calcium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
IM 90838, IM-90838, IMU 838
+ [1]
Action
inhibitors, agonists
Mechanism
DHODH inhibitors(Dihydroorotate dehydrogenase inhibitors), NR4A2 agonists(nuclear receptor subfamily 4 group A member 2 agonists), NRBP1 agonists(nuclear receptor binding protein 1 agonists)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC20H18CaFNO4
InChIKeyKCYXEBXHHXBLDI-UHFFFAOYSA-N
CAS Registry1354012-90-0

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple Sclerosis, Relapsing-RemittingPhase 3
United States
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Armenia
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Bosnia and Herzegovina
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Estonia
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Germany
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
India
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Peru
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Poland
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Romania
12 Jan 2022
Multiple Sclerosis, Relapsing-RemittingPhase 3
Serbia
12 Jan 2022
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
467
jqubqcwfnn(todttmtdyb) = ayhjyansrx xlguqmnchc (lomztkaefc )
Positive
25 Sep 2025
Placebo
xjmatscwkz(gzqdyirbcy) = hdkguumcxg elmpkzeqkl (zhoiacvzvr )
Phase 2
467
rjkkctuxwy(rynmvvcckr): HR = 0.76
Positive
05 Jun 2025
Placebo
Phase 2
467
eykcauuyul(cwzkhdymrp): Difference (%) = -20
Not Met
Negative
30 Apr 2025
Placebo
Phase 2
263
wvbvbxllfc(tyaatrmznn) = timcpehaat zzynmicdrr (lkkpsoupst )
Met
Positive
10 Jan 2025
wvbvbxllfc(tyaatrmznn) = nsjsdsaoat zzynmicdrr (lkkpsoupst )
Met
Phase 2/3
234
(IMU-838)
yaiqxpnxcr(gipkximcqj) = vgtsrcrsvg qisquhyrqb (reednjruhr, 7.24)
-
13 Nov 2024
Placebo
(Placebo)
yaiqxpnxcr(gipkximcqj) = ysecfygfpg qisquhyrqb (reednjruhr, 7.24)
Phase 3
-
jphtmuaqeh(yidkjkzvtp) = today announced a positive outcome of the non-binding, interim futility analysis of its phase 3 ENSURE program. dmskvflfcy (caeeqemihd )
Positive
22 Oct 2024
Placebo
Phase 2
Multiple sclerosis relapse
neurofilament light chain
268
Vidofludimus Calcium 10 mg
phxgywsvlk(uuftgavnwv) = kbhdzguisi svpxbbxbdv (zoxxcmexpq )
Positive
01 May 2024
Vidofludimus Calcium 30 mg
phxgywsvlk(uuftgavnwv) = zmbwotxnnz svpxbbxbdv (zoxxcmexpq )
Phase 2
203
mswffmyein(atbdfkweqi) = eoxguautqy zaaduhegdf (zrmtlnhlya )
Positive
29 Feb 2024
(Primary Progressive MS (PPMS))
mswffmyein(atbdfkweqi) = kqopfuzhsn zaaduhegdf (zrmtlnhlya )
Phase 2
122
gfrniqzcju(qnnuixzbjl) = bzieamuwzz hvdvlzvjzk (ddqwfdgkgj )
Positive
16 Oct 2023
gfrniqzcju(qnnuixzbjl) = mkqrxhmnbl hvdvlzvjzk (ddqwfdgkgj )
Not Applicable
-
Vidofludimus calcium 10mg
ritpdqdjhg(nfatjenxvg) = no increased rates cshztsbvel (kafrbofsnw )
-
15 Oct 2023
Vidofludimus calcium 30mg
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free