Last update 01 Nov 2024

AZD-4877

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
Mechanism
KIF11 inhibitors(Kinesin-like protein 1 inhibitors)
Therapeutic Areas
Active Indication
Inactive Organization
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC28H33N5O2S
InChIKeySMFXSYMLJDHGIE-UHFFFAOYSA-N
CAS Registry758722-49-5

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Urothelial carcinoma recurrentPreclinical
DE
01 May 2008
Ureteral NeoplasmsDiscovery
ES
01 May 2008
Ureteral NeoplasmsDiscovery
DE
01 May 2008
Ureteral NeoplasmsDiscovery
CA
01 May 2008
Ureteral NeoplasmsDiscovery
GB
01 May 2008
Ureteral NeoplasmsDiscovery
US
01 May 2008
Urothelial carcinoma recurrentDiscovery
US
01 May 2008
Urothelial carcinoma recurrentDiscovery
ES
01 May 2008
Urothelial carcinoma recurrentDiscovery
GB
01 May 2008
Urothelial carcinoma recurrentDiscovery
CA
01 May 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
39
(hputshixtj) = 6 patients wmeyabugqj (lnyhnxlyhb )
Negative
01 Aug 2013
Phase 1/2
47
(ppqbosdizg) = lswnulkwhn roppmilwci (unsawyhrpg )
Negative
01 Jun 2012
Phase 2
54
pubfcyrwho(kozxutryim) = gbxuzxztnz ouaxwkojyv (lvymjmydiq, weqhhuygwd - lxeyzymshm)
-
12 Jan 2011
Phase 1
24
(fhzwwdvjbx) = Mucositis was the DLT at 18 mg/day; with 1 pt developing Gr 3 palmar-plantar syndrome at this dose mdsmputwog (kgxfzxphzs )
-
20 May 2009
Phase 1
-
(bqmoesjfyu) = egzmwsamht sdvlhjqova (fnvphubevn )
-
20 May 2008
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Core Patent

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Clinical Trial

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Approval

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Regulation

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