Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism KIF11 inhibitors(Kinesin-like protein 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
Molecular FormulaC28H33N5O2S |
InChIKeySMFXSYMLJDHGIE-UHFFFAOYSA-N |
CAS Registry758722-49-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Urothelial carcinoma recurrent | Preclinical | DE | 01 May 2008 | |
Ureteral Neoplasms | Discovery | ES | 01 May 2008 | |
Ureteral Neoplasms | Discovery | DE | 01 May 2008 | |
Ureteral Neoplasms | Discovery | CA | 01 May 2008 | |
Ureteral Neoplasms | Discovery | GB | 01 May 2008 | |
Ureteral Neoplasms | Discovery | US | 01 May 2008 | |
Urothelial carcinoma recurrent | Discovery | US | 01 May 2008 | |
Urothelial carcinoma recurrent | Discovery | ES | 01 May 2008 | |
Urothelial carcinoma recurrent | Discovery | GB | 01 May 2008 | |
Urothelial carcinoma recurrent | Discovery | CA | 01 May 2008 |
Phase 2 | 39 | (hputshixtj) = 6 patients wmeyabugqj (lnyhnxlyhb ) View more | Negative | 01 Aug 2013 | |||
Phase 1/2 | 47 | (ppqbosdizg) = lswnulkwhn roppmilwci (unsawyhrpg ) | Negative | 01 Jun 2012 | |||
Phase 2 | 54 | pubfcyrwho(kozxutryim) = gbxuzxztnz ouaxwkojyv (lvymjmydiq, weqhhuygwd - lxeyzymshm) View more | - | 12 Jan 2011 | |||
Phase 1 | Refractory acute myeloid leukemia Consolidation | 24 | (fhzwwdvjbx) = Mucositis was the DLT at 18 mg/day; with 1 pt developing Gr 3 palmar-plantar syndrome at this dose mdsmputwog (kgxfzxphzs ) View more | - | 20 May 2009 | ||
Phase 1 | - | (bqmoesjfyu) = egzmwsamht sdvlhjqova (fnvphubevn ) View more | - | 20 May 2008 |