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Last update 31 Mar 2025
Encofosbuvir
Last update 31 Mar 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms Yiqibuvir, 英强布韦, HEC 110114 + [3] |
Target |
Action inhibitors |
Mechanism NS5B polymerase inhibitors(Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date China (25 Mar 2025), |
Regulation- |
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Structure/Sequence
Molecular FormulaC30H42FN4O13PS |
InChIKeyGAHCKEWMXZYJAZ-VBWBMHESSA-N |
CAS Registry2232134-77-7 |
Related
12
Clinical Trials associated with EncofosbuvirNCT05998304
Single Dose Absorption, Distribution, Metabolism, and Excretion Study of [14C] Yiqibuvir in Healthy Male Participants
CTR20232368
中国成年男性健康受试者单次口服[14C]英强布韦的体内物质平衡研究
[Translation] Study on the balance of substances in the body after a single oral dose of [14C]-inqiangbuvir in healthy adult male subjects in China
NCT05504876
A Single-center, Open-label Study to Investigate the Effect of a Single Oral Dose of HEC74647 and HEC110114 on the Pharmacokinetics of Midazolam, and Their Metabolites in Healthy Subjects
100 Clinical Results associated with Encofosbuvir
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100 Translational Medicine associated with Encofosbuvir
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100 Patents (Medical) associated with Encofosbuvir
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100 Deals associated with Encofosbuvir
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R&D Status
Approved
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Hepatitis C, Chronic | China | 25 Mar 2025 |
Developing
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Hepatitis C | Phase 1 | China | 03 Aug 2023 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Literature Manual  | Phase 2 | 120 | uvpwrndqre(wegdntjjpd) = zvamgffuzd eauhjhgzgw (insqrqacgo ) View more | Positive | 20 Jul 2024 | ||
uvpwrndqre(wegdntjjpd) = ontfxhovbz eauhjhgzgw (insqrqacgo ) View more |
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