Last update 24 May 2025

SG-1827

Overview

Basic Info

Drug Type
Fc fusion protein
Synonyms
SG 1827, SG1827
Target
CD28 x CTLA4
Action
modulators, stimulants
Mechanism
CD28 modulators(T-cell-specific surface glycoprotein CD28 modulators), CTLA4 modulators(Cytotoxic T-Lymphocyte-Associated Antigen 4 modulators), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Hangzhou Shangjian Biotechnology Co., Ltd.Hangzhou Shangjian Biotechnology Co., Ltd.
Active Organization
Hangzhou Shangjian Biotechnology Co., Ltd.Hangzhou Shangjian Biotechnology Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with SG-1827
NCT06076291
/ RecruitingPhase 1
A Phase I Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SG1827 in Subjects With Advanced Solid Tumors
100 Clinical Results associated with SG-1827
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100 Translational Medicine associated with SG-1827
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100 Patents (Medical) associated with SG-1827
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100 Deals associated with SG-1827
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Hangzhou Shangjian Biotechnology Co., Ltd.Hangzhou Shangjian Biotechnology Co., Ltd.
19 Sep 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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