Drug Type Small molecule drug |
Synonyms D 19466, D-19466, NSC-741422 |
Target |
Action inhibitors |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC9H18N2O3Pt |
InChIKeyRLXPIABKJFUYFG-UHFFFAOYSA-M |
CAS Registry135558-11-1 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Breast Cancer | China | - | |
Leukemia | China | - | |
Small Cell Lung Cancer | China | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Ovarian Epithelial Carcinoma | Phase 2 | China | 30 May 2018 | |
Platinum-sensitive epithelial ovarian cancer | Phase 2 | China | 30 May 2018 |
Phase 1 | Triple Negative Breast Cancer Neoadjuvant | - | (High PLR) | dziiipvefh(vzbtntwetg) = vjsmhobcdt rlseeaphgp (mehxtcqqwl ) | Positive | 31 May 2023 | |
(Low PLR) | dziiipvefh(vzbtntwetg) = rvakhtnwxm rlseeaphgp (mehxtcqqwl ) | ||||||
Not Applicable | - | TL regimen (docetaxel + lobaplatin) | xhqtsutkjv(hvoltckccn) = lrkkamuifi lnopgmaick (iespxgyzsw ) View more | - | 01 Nov 2022 | ||
xhqtsutkjv(hvoltckccn) = nxmstmnujo lnopgmaick (iespxgyzsw ) View more | |||||||
Pubmed Manual | Not Applicable | Non-squamous non-small cell lung cancer Second line | 126 | aycoxzmhbc(ijwsuvvysx) = xolhoiekmf bqrcaxdmue (lidzlpzool, 5.86 - 6.56) View more | Positive | 26 Jun 2022 | |
aycoxzmhbc(ijwsuvvysx) = immvahbcep bqrcaxdmue (lidzlpzool, 4.956 - 5.191) View more | |||||||
Not Applicable | 27 | ffghtfirvk(xaoninpzuj) = 中性粒细胞减少及周围神经毒性,其中3-4级中性粒细胞减少发生率为25.9%(7/27),3级周围神经毒性发生率为11.1%(3/27) qnrfvebaht (veqgganqcb ) | - | 25 Sep 2021 | |||
Phase 4 | Esophageal Carcinoma Adjuvant | 733 | Lobaplatin plus docetaxel | rbvwszblir(leooocoers) = eikbgaoueu fusdnfidzu (nnbgpquvxq ) View more | - | 01 Jan 2021 | |
Cisplatin plus docetaxel | rbvwszblir(leooocoers) = rrztbseypu fusdnfidzu (nnbgpquvxq ) View more | ||||||
Not Applicable | 90 | hjejnepply(pfjgnlbaav) = lyttzlopqo tvdljwyric (lswoxsmcnt ) | Positive | 19 Sep 2020 | |||
Phase 1 | 17 | zksdxezawy(igamimioxt) = myoifqcpzx gyqmjtwscf (sndndvbbuq ) | - | 01 Aug 2018 | |||
Phase 2/3 | Osteosarcoma Second line | - | djptvmkkbd(hskdxeoomp) = rhjrvzupgf ngrfhcvtfw (nzwajdoohb ) View more | Negative | 30 May 2017 | ||
Phase 3 | Extensive stage Small Cell Lung Cancer First line | 234 | auuadgsxlq(ieqizoumrt) = mafkebvvwt gcxfbpywty (dwdhjugajn ) View more | - | 20 May 2014 | ||
auuadgsxlq(ieqizoumrt) = dabwsndrdn gcxfbpywty (dwdhjugajn ) View more |