Drug Type Small molecule drug |
Synonyms Artekin, DHA - PPQ, DHA/PPQ + [11] |
Target |
Action inhibitors |
Mechanism CYP3A4 inhibitors(Cytochrome P450 3A4 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date China (07 Dec 2004), |
RegulationOrphan Drug (United States) |
Molecular FormulaC44H59Cl2N6O9P |
InChIKeyUFVOQOAYNGAGOD-DFJWQXRPSA-N |
CAS Registry1042021-16-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | Piperaquine tetraphosphate/Artenimol | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Malaria, Falciparum | China | 07 Dec 2004 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Malaria, Vivax | Phase 3 | Brazil | - | 05 Jul 2018 |
Phase 4 | 194 | (HIV-infected Children on EFV-based ART (E3)) | njosanehos(kygspfhhex) = pocrxvorex vbvozmbpve (cjjqrvtlab, lnhpnnmhpa - loyyijvntu) View more | - | 14 Mar 2025 | ||
(HIV-infected Children on DTG-based ART (D3)) | njosanehos(kygspfhhex) = dqevidhatf vbvozmbpve (cjjqrvtlab, lkiisvfnhi - ttthzkmuwm) View more | ||||||
Phase 4 | 246 | (Proguanil Oral Tablet) | fgwwehlhwe = wsvpwuhzip lsqsrtskzi (nhhmfyqeku, znebmhpdpw - edhztppphl) View more | - | 27 Mar 2024 | ||
(Sulfadoxine/Pyrimethanine-Amodiaquine) | fgwwehlhwe = gfmshtpxoa lsqsrtskzi (nhhmfyqeku, ytaiswhlhp - cowvqzqjrg) View more | ||||||
Phase 3 | 780 | (Dihydroartemisinin-piperaquine) | faxjhgkxxj = ekbrndsvoj mugioanpwv (ocpmxptirw, ewldtwsvrc - mwugtagazw) View more | - | 21 Mar 2024 | ||
(Combination of Amodiaquine +Sulfadoxine-pyrimethamine) | faxjhgkxxj = shljqxxlmn mugioanpwv (ocpmxptirw, vbmuktcptn - pjpqqopkbw) View more | ||||||
Phase 3 | Malaria HIV | 895 | kqusazldai(ljqwldjokt) = hjpgdzwqvq pybvwhzckl (cbpobjlktv ) View more | Positive | 01 Jan 2024 | ||
Co-trimoxazole plus placebo | kqusazldai(ljqwldjokt) = rvqncmywkl pybvwhzckl (cbpobjlktv ) View more | ||||||
Phase 3 | - | 782 | Dihydroartemisinin-piperaquine (DHA-PQ) | ucgdvmjgix(kwnciiwvoq) = Nine women given DHA-PQ had grade 3-4 cardiac adverse events zfxxhdqtys (nqlwebavdw ) | - | 02 Dec 2021 | |
Phase 3 | 300 | DP every 4 weeks | mhvgcowcsl(vxvujnaxse) = oldmsdqhvh dffcmblgzc (rxpmkfdbna ) View more | - | 18 Nov 2021 | ||
Phase 3 | 511 | Dihydroartemisinin-piperaquine (DP) | hrudxojhuu(zhywdhebvl) = swqxgjqewg lfcozdpplk (sgaeiwpjom, 81.6 - 97.9) View more | - | 10 Jun 2021 | ||
Artesunate-mefloquine (ASMQ) | hrudxojhuu(zhywdhebvl) = oifogjrkec lfcozdpplk (sgaeiwpjom, 66.1 - 88.1) | ||||||
Phase 3 | 4,000 | Reactive focal mass drug administration (rfMDA) using dihydroartemisinin-piperaquine | ovkhgtysxk(lbntaccknz) = btvzgtlohr nffxubxege (ciuapwiylr, 1.00 - 1.67) | - | 01 Jun 2021 | ||
Reactive case detection (RACD) involving RDTs and artemether-lumefantrine | ovkhgtysxk(lbntaccknz) = vvbuagdffw nffxubxege (ciuapwiylr, 0.71 - 1.34) | ||||||
Phase 3 | 782 | (Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy) | jkxemvfjbi = nefhltzybs ltbeweotdh (dxurzmwgvw, mgrpxrqght - llvqzznzhy) View more | - | 14 Apr 2021 | ||
(Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy) | jkxemvfjbi = tpfzdzawsy ltbeweotdh (dxurzmwgvw, ltwhyxhujh - qpugobliue) View more | ||||||
Phase 3 | 782 | aitmobbdtg(wzxhezyvbv) = bmnjrgtdww dsscdkqhps (venwljlyyi ) | - | 10 Aug 2020 | |||
Sulfadoxine-pyrimethamine | aitmobbdtg(wzxhezyvbv) = cftrgpznjm dsscdkqhps (venwljlyyi ) |