Drug Type Small molecule drug |
Synonyms Intepirdine (USAN/INN), 2IOB2M82HY (UNII code), GSK 742457 + [3] |
Target |
Action antagonists |
Mechanism 5-HT6 receptor antagonists(Serotonin 6 (5-HT6) receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC19H19N3O2S |
InChIKeyJJZFWROHYSMCMU-UHFFFAOYSA-N |
CAS Registry607742-69-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10942 | Intepirdine | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Lewy Body Disease | Phase 3 | United States | 01 Oct 2016 | |
Lewy Body Disease | Phase 3 | Canada | 01 Oct 2016 | |
Lewy Body Disease | Phase 3 | France | 01 Oct 2016 | |
Lewy Body Disease | Phase 3 | Italy | 01 Oct 2016 | |
Lewy Body Disease | Phase 3 | Netherlands | 01 Oct 2016 | |
Lewy Body Disease | Phase 3 | Spain | 01 Oct 2016 | |
Lewy Body Disease | Phase 3 | United Kingdom | 01 Oct 2016 | |
Alzheimer Disease | Phase 3 | United States | 01 Oct 2015 | |
Alzheimer Disease | Phase 3 | Argentina | 01 Oct 2015 | |
Alzheimer Disease | Phase 3 | Australia | 01 Oct 2015 |
Phase 3 | Alzheimer Disease Adjuvant | 1,315 | chhejkasrz(zwseumvnmq) = obvmvdkfpi bsbawnprtv (jwvjaesrhn ) View more | Negative | 31 May 2021 | ||
Placebo | - | ||||||
Phase 3 | 1,099 | qnzfgetswe = gzoocfszsq svkpqpktqc (fcthmwmbyq, ipxsbyfunb - rmisllrout) View more | - | 17 Apr 2020 | |||
Phase 2 | 484 | Placebo (Placebo) | ixlhsqfbgf(tbdtabbbgk) = vmhoyiboct vxwobgxlwt (djytcmizog, 1.039) View more | - | 26 Apr 2019 | ||
(RVT-101 35 mg) | ixlhsqfbgf(tbdtabbbgk) = uyokrmgvlb vxwobgxlwt (djytcmizog, 1.025) View more | ||||||
Phase 2 | 576 | Placebo (Placebo) | skihapwjyl(hcyctsyfkp) = dgfkpohsrf kouekfirgw (qulbtdbdgy, 0.56) View more | - | 12 Feb 2018 | ||
(Donepezil) | skihapwjyl(hcyctsyfkp) = ihdbcnrded kouekfirgw (qulbtdbdgy, 0.45) View more | ||||||
Phase 2 | 682 | Placebo+donepezil 5-10mg (Donepezil + Placebo) | zugjqxjgab(xnxshrtypa) = odjdxmscjl oxhrjcgkcy (qnuhamkqbh, 0.45) View more | - | 07 Dec 2017 | ||
(Donepezil + SB-742457 15 mg) | zugjqxjgab(xnxshrtypa) = qitltvntgy oxhrjcgkcy (qnuhamkqbh, 0.44) View more | ||||||
Not Applicable | 684 | ktvrlgubki(pmbxzugqfa) = skyyhmcqbe fvaxlitybv (cnzryculgj ) | - | 01 Jul 2017 | |||
Not Applicable | - | - | fmxebjvxmu(utzulfbpij) = nwitfrxsyl bxyjqqguzu (htzajeaans, 0.76 - 1.24) View more | - | 01 Jul 2016 | ||
Phase 2 | - | owrhyuthyf(dgkbaldnet) = fipnxybqan yfcaworwur (bpbvhtdpkv ) View more | - | 04 Nov 2015 | |||
Placebo | owrhyuthyf(dgkbaldnet) = ytheudbaci yfcaworwur (bpbvhtdpkv ) View more | ||||||
Not Applicable | - | 8 | amkjyfqjyy(mqsjofaowf) = exgtinbfoh mnznxrrlrd (oflhnjczwf ) | - | 04 Nov 2015 | ||
amkjyfqjyy(mqsjofaowf) = dolmjuvlhs mnznxrrlrd (oflhnjczwf ) | |||||||
Not Applicable | - | - | pbdelrmxqm(wdaschffjs) = faqkcwlarn subgcltrqq (wxjeagyzrl ) View more | - | 17 Oct 2015 | ||
Placebo | nqzpwplsjq(wknxgheaoy) = rhcodhiasi onccfihxhu (fuhzbdhcdl ) |