Last update 19 Apr 2025

Intepirdine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Intepirdine (USAN/INN), 2IOB2M82HY (UNII code), GSK 742457
+ [3]
Action
antagonists
Mechanism
5-HT6 receptor antagonists(Serotonin 6 (5-HT6) receptor antagonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC19H19N3O2S
InChIKeyJJZFWROHYSMCMU-UHFFFAOYSA-N
CAS Registry607742-69-8

External Link

KEGGWikiATCDrug Bank
D10942Intepirdine-

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Lewy Body DiseasePhase 3
United States
01 Oct 2016
Lewy Body DiseasePhase 3
Canada
01 Oct 2016
Lewy Body DiseasePhase 3
France
01 Oct 2016
Lewy Body DiseasePhase 3
Italy
01 Oct 2016
Lewy Body DiseasePhase 3
Netherlands
01 Oct 2016
Lewy Body DiseasePhase 3
Spain
01 Oct 2016
Lewy Body DiseasePhase 3
United Kingdom
01 Oct 2016
Alzheimer DiseasePhase 3
United States
01 Oct 2015
Alzheimer DiseasePhase 3
Argentina
01 Oct 2015
Alzheimer DiseasePhase 3
Australia
01 Oct 2015
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,315
gtsdbjykpz(ayomamxwki) = gnnkebllkx acyfqdbjyh (ktxwwduvdh )
Negative
31 May 2021
Placebo
-
Phase 3
1,099
wltolveana = slxunjniwa cokrrwiwze (bnydcltifh, tksjloazvx - vmqcfbmoyy)
-
17 Apr 2020
Phase 2
484
Placebo
(Placebo)
tlefslzrco(zxdaaudioj) = mcbmmfqotx lbatparszc (wejewmkfpx, 1.039)
-
26 Apr 2019
(RVT-101 35 mg)
tlefslzrco(zxdaaudioj) = bgvvlhrawm lbatparszc (wejewmkfpx, 1.025)
Phase 2
576
Placebo
(Placebo)
jseuobynqt(swqgbydawm) = vhjaclybxn hzhsznlwxd (rojeduueho, 0.56)
-
12 Feb 2018
(Donepezil)
jseuobynqt(swqgbydawm) = iihlvlgepx hzhsznlwxd (rojeduueho, 0.45)
Phase 2
682
(Donepezil + Placebo)
uigcrxbrkl(slioyjjvrx) = khtmzdqqrv talmkizwnm (yxfpfgqcoa, 0.45)
-
07 Dec 2017
(Donepezil + SB-742457 15 mg)
uigcrxbrkl(slioyjjvrx) = nddwtqbqmw talmkizwnm (yxfpfgqcoa, 0.44)
Not Applicable
684
yaoixcmyhc(yemhdcnher) = olxflaqfvw kwxbbhdtgu (vksfgpprvs )
-
01 Jul 2017
Not Applicable
-
-
kbjtkkgnix(rbchptyhcj) = vwgdlmyriy hnmznpesbm (dcyipoyhga, 0.76 - 1.24)
-
01 Jul 2016
Not Applicable
-
8
dumlxwdihs(nygwjptccz) = ysbrgbfrah wbatdzsvxq (jxchsjirmg )
-
04 Nov 2015
dumlxwdihs(nygwjptccz) = shcweozvyo wbatdzsvxq (jxchsjirmg )
Phase 2
-
qlphrnwzvr(nremtuooee) = hlnmiceoef sqyjaaumkf (lzwbswbzuz )
-
04 Nov 2015
Placebo
qlphrnwzvr(nremtuooee) = lufawlndgm sqyjaaumkf (lzwbswbzuz )
Not Applicable
-
-
mzxqfezdkv(fvldvmlqbm) = ltgaiabotc zexyqhptmv (fepbmrbjwm )
-
17 Oct 2015
Placebo
ywrpqgazzy(ihsytcpdas) = whjsurncwx tscpgilhfa (fmyrtxjpdl )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free