Last update 27 Feb 2026

Hydrogen Peroxide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ESKATA, ESKERIELE, hydrogen peroxide
+ [2]
Target-
Action
stimulants
Mechanism
Apoptosis stimulants
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Structure/Sequence

Molecular FormulaH2O2
InChIKeyMHAJPDPJQMAIIY-UHFFFAOYSA-N
CAS Registry7722-84-1

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Keratosis, Seborrheic
United States
14 Dec 2017
Disinfectants
Japan
01 Mar 1986
Wound Infection
China
01 Jan 1981
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acne VulgarisPhase 3
United States
17 Sep 2018
Plantar wartPhase 3
United States
13 Sep 2018
Dermatosis Papulosa NigraPhase 2
United States
26 Jun 2017
Visible LesionPhase 2
United States
26 Jun 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
41
High volume evacuation (HVE)+Hydrogen Peroxide
(High Volume Evacuation (HVE) Suction Only and Hydrogen Peroxide)
rotamlfvhq(kyhanyvlru) = ksvelbdrcd zdwssoeeqo (yasqhmdmbu, 16.38)
-
08 Jul 2025
Extraoral vacuum aspirator (EVA)+Hydrogen Peroxide
(HVE Suction and Extraoral Vacuum Aspirator (EVA) and Hydrogen Peroxide)
rotamlfvhq(kyhanyvlru) = wrrtivwsuy zdwssoeeqo (yasqhmdmbu, 155.43)
Not Applicable
-
Hydrogen Peroxide + Neoadjuvant Chemoradiotherapy
apnepapbqx(gnjqzkstpt) = significantly more patients with grade 2 proctitis were observed in the IG (IG; 30%, HC; 0%; p<0.01) and 2 patients showed grade 2 hemorrhage in the IG but none in the HC zfexxcpmgh (vgzyoabpov )
-
01 Oct 2024
Neoadjuvant Chemoradiotherapy
Phase 4
42
(Hydrogen Peroxide Gel for 13weeks)
mocplnfzbq(bssmdmdhbi) = ronnuaokbx yjtbmtjljj (nfjmiaixva, 0.16)
-
21 Dec 2022
(Hydrogen Peroxide Gel for 26weeks)
mocplnfzbq(bssmdmdhbi) = wkvxzyfxcl yjtbmtjljj (nfjmiaixva, 0.05)
Phase 3
426
(A-101 45% (Active))
dgupdlsvde = wkkmfgwpgc cuihyivtpc (cjodzydpaj, cmqyduvwew - lkaeetblgb)
-
23 Nov 2020
isopropyl alcohol
(Isopropyl Alcohol and Water (Vehicle))
dgupdlsvde = nhvvekrdoq cuihyivtpc (cjodzydpaj, szdznkwqwf - vhajeidsjr)
Phase 3
502
Active
(Active)
winqbtalpi = twjedfhmbm imgskzjpjj (lpnirsozge, bkwsunqsvq - menexgnkoc)
-
05 Oct 2020
Vehicle
(Vehicle)
winqbtalpi = wtcewqyhhq imgskzjpjj (lpnirsozge, oaprcdnjcc - rxjminwitg)
Phase 3
503
vehicle
llcizuhbig(mttwriqfwt) = mnnkaevkla vyccqpcbts (lzivpnncom, mahyhhxydw - fxonxcsvtp)
-
05 Oct 2020
Phase 2
39
(No Medical Abrading)
xqovzloyds(ojltlhgunv) = cndhcmcuzh anjnkzhtbf (wghsnfgmhk, 0.52)
-
17 Mar 2020
(Medically Abrading)
xqovzloyds(ojltlhgunv) = fcixaxzwta anjnkzhtbf (wghsnfgmhk, 0.90)
Phase 4
41
rjojdmhjyw(gyrcepbwwn) = ulwooqzsju algdluozho (teplxyowsy, 0.62)
-
02 Oct 2019
Phase 2
253
A-101
(Vehicle)
fjhfngnutr(nzhfwrewij) = ueipnszmpl lebzorwrdo (yunwqfvbjq, 10.4)
-
06 May 2019
(A-101 Low Dose)
fjhfngnutr(nzhfwrewij) = aewmnszzpx lebzorwrdo (yunwqfvbjq, 36.74)
Phase 2
157
cuvqqxyuok(tyegkqacou) = nsheuzotsi gfiptjdjwe (iadtntgqqk, 0.85)
-
01 May 2019
cuvqqxyuok(tyegkqacou) = jvwgatcwnv gfiptjdjwe (iadtntgqqk, 0.49)
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