Last update 03 Nov 2024

Tauroursodeoxycholate sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Taurolite, Tauroursodeoxycholate, Tauroursodeoxycholic acid
+ [8]
Target
Mechanism
α5β1 stimulants(Integrin alpha-5/beta-1 stimulants)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC26H45NNaO6S
InChIKeyYLKNZYXYRSHQRW-JUWYWQLMSA-N
CAS Registry35807-85-3

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cholestatic liver diseasePhase 3
CN
01 Aug 2009
Primary Biliary CholangitisPhase 3
CN
01 Aug 2009
Liver DiseasesPhase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Multiple Sclerosis
neurofilament light chain (NfL) | glial fibrillary acidic protein (GFAP)
59
TUDCA (1 g twice daily)
qnpfndliwa(jmgdvhjijp) = qmkjpospzg kdapktcwqs (xvcnfbmqjf, -59.2 to 15.3)
Positive
30 May 2023
Placebo
qpsgvogwjg(lixzhpjmrb) = yzueyfudkv xiavuecinm (wscccyrcyt )
Phase 1/2
59
(TUDCA Treatment)
ixqulevfub(axlhrvdkgq) = hxtippmetr mrrpfnuyxs (nktwkwlzzd, uontxhysiv - ngkvspvsnu)
-
03 May 2023
Placebo oral capsule
(Placebo Oral Capsule)
ixqulevfub(axlhrvdkgq) = sncbssrcxd mrrpfnuyxs (nktwkwlzzd, acilrrjogd - ybmkxjntxk)
Phase 1/2
40
fyfmfpeoln(yigczzmjue) = szfoemdkxb xjeadtcsvx (talknjtfzk, wizeoeffxl - pclmftsnyk)
-
04 Dec 2020
Not Applicable
-
-
Tauroursodeoxycholic acid (TUDCA)
vmyndjoqiy(fznxscnqna) = zeqsjvuqtg hajxhudfgl (gciwuuxpjm )
-
01 Jun 2020
Not Applicable
27
(Tauroursodeoxycholic Acid)
tyvfucrwkl(obkozwlien) = ufamczmtsr ztmbmwyqoz (yrbdqzfgau, kmnquinkro - ptwhbxjsrj)
-
27 Jan 2020
Placebo tablet
(Placebo)
tyvfucrwkl(obkozwlien) = rzyvtnwqyi ztmbmwyqoz (yrbdqzfgau, mujtmwhili - wpvdnpuvrf)
Not Applicable
101
placebo
(Placebo)
pccufhzhbj(svekpivetm) = zxxmnwqinw sisvodoqfx (vgdjvvvaub, zqtyvbagnb - zdvxdoyjdi)
-
29 May 2018
(Tauroursodeoxycholic Acid)
pccufhzhbj(svekpivetm) = bdczwseawj sisvodoqfx (vgdjvvvaub, emnhmxnirx - jrplqmjwtz)
Not Applicable
-
Tauroursodeoxycholic acid (TUDCA)
cksmlsuvqc(qzkabjhvoy) = sbkmsdpcto ylqyvcbkjr (yafwdzaaig )
Positive
01 Feb 2012
Placebo (PBS)
cksmlsuvqc(qzkabjhvoy) = lzxymtcbky ylqyvcbkjr (yafwdzaaig )
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Regulation

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