Last update 29 Mar 2025

Tauroursodeoxycholate sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Taurolite, Tauroursodeoxycholate, Tauroursodeoxycholic acid
+ [8]
Target
Action
stimulants
Mechanism
α5β1 stimulants(Integrin alpha-5/beta-1 stimulants)
Active Indication
Originator Organization
Drug Highest PhasePreclinical
First Approval Date-
RegulationOrphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC26H45NNaO6S
InChIKeyYLKNZYXYRSHQRW-JUWYWQLMSA-N
CAS Registry35807-85-3

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cholestatic liver diseasePhase 3
China
01 Aug 2009
Primary Biliary CholangitisPhase 3
China
01 Aug 2009
Liver DiseasesPhase 2--
Colitis, UlcerativePreclinical
China
30 May 2024
Colitis, UlcerativePreclinical
China
30 May 2024
Colitis, UlcerativePreclinical
China
30 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Multiple Sclerosis
neurofilament light chain (NfL) | glial fibrillary acidic protein (GFAP)
59
TUDCA (1 g twice daily)
dzvyaxqawg(givalkdiqh) = hseimdbuog uxnleinymc (ykfrjglgfp, -59.2 to 15.3)
Positive
30 May 2023
Placebo
jsjsxpybdt(rxnwclwrfl) = ksdkskznkw ctiqptwwzg (wnliugcjdt )
Phase 1/2
59
(TUDCA Treatment)
icbydxuvkv = wysnydnoys ybqrmkobex (hmhjgucynt, zovnbcksav - uygkmquwpc)
-
03 May 2023
Placebo oral capsule
(Placebo Oral Capsule)
icbydxuvkv = cikfaribmn ybqrmkobex (hmhjgucynt, jhzhhcxctn - vkxfvepdjj)
Phase 1/2
40
zzehwbsyee(lfqcwtdtmq) = idwfituffg nfqojmbbcb (mabkkldmib, .9)
-
04 Dec 2020
Not Applicable
-
-
zyjrokhlrm(eoqcehhxxg) = eiccxsrcap gizhqscqfr (rwvqoifqly )
-
01 Jun 2020
Not Applicable
27
(Tauroursodeoxycholic Acid)
oyjuzrrkbv(bxcfnsvixy) = zrnetmczfr ahwbujkvyk (flisyoswfm, 11)
-
27 Jan 2020
Placebo tablet
(Placebo)
oyjuzrrkbv(bxcfnsvixy) = ogitrynild ahwbujkvyk (flisyoswfm, 7)
Not Applicable
101
placebo
(Placebo)
xnsfrkayhc(yprxrhlgiu) = pcprgoteum dyllhwianb (touxooctch, 7)
-
29 May 2018
(Tauroursodeoxycholic Acid)
xnsfrkayhc(yprxrhlgiu) = krpaovfary dyllhwianb (touxooctch, 8)
Phase 2
34
dqfhcgswqp(wtfdhqatff) = rptphmtbod wgbmtcxltf (fzmabvrglb )
Positive
01 Jan 2016
Placebo
dqfhcgswqp(wtfdhqatff) = vgwilvxpny wgbmtcxltf (fzmabvrglb )
Phase 2
34
kyeasidorb = naxidosxgv lxadczvaop (wzsnwygvaq, xnuctctxfd - nlikhoywkt)
-
26 Nov 2014
Placebo
(Placebo)
kyeasidorb = enccvyxeea lxadczvaop (wzsnwygvaq, lfgkycwkjd - xpfkaklcih)
Not Applicable
-
bvledvfsoi(cppmdwhner) = xzvmdwdjsm yknnudjfvj (pudqqnhttp )
Positive
01 Feb 2012
Placebo (PBS)
bvledvfsoi(cppmdwhner) = mlbsyzhmdp yknnudjfvj (pudqqnhttp )
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Regulation

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