Last update 12 Dec 2024

Envonalkib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
依奉阿克, CT-1139, TQ B3139
+ [1]
Mechanism
ALK inhibitors(Anaplastic lymphoma kinase inhibitors), ROS1 inhibitors(Proto-oncogene tyrosine-protein kinase ROS inhibitors), c-Met inhibitors(Hepatocyte growth factor receptor inhibitors)
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC24H26Cl2FN5O2
InChIKeyBVGDAZBTIVRTGO-UONOGXRCSA-N
CAS Registry1621519-26-3

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
ALK positive Non-Small Cell Lung Cancer
CN
11 Jun 2024
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MET gene amplification Non-small Cell Lung CancerPhase 2
CN
11 Aug 2020
Advanced Malignant Solid NeoplasmPhase 1
CN
01 Feb 2021
Advanced cancerPhase 1
CN
12 Jul 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
264
csxvdwsvns(bbpbsqbley) = wpfogqundt lutbyzdloz (ntpcareklz )
Positive
14 Aug 2023
csxvdwsvns(bbpbsqbley) = ytwejufsiy lutbyzdloz (ntpcareklz )
Phase 3
264
Envonalkib 600mg
(overall)
unbafnwjbt(phklwsqpjc) = dgspeortmx vcntoyzgid (ihyuipawnk )
Superior
03 Dec 2022
unbafnwjbt(phklwsqpjc) = lovuddfqmb vcntoyzgid (ihyuipawnk )
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Approval

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Regulation

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