Last update 21 Nov 2024

Colecalciferol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+)-vitamin D3, (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
+ [29]
Target
Mechanism
VDR agonists(Vitamin D receptor agonists)
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Structure

Molecular FormulaC27H44O
InChIKeyQYSXJUFSXHHAJI-YRZJJWOYSA-N
CAS Registry67-97-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Vitamin D Deficiency
CN
01 Jan 1987
Familial Hypophosphatemic Rickets
CA
-01 Jan 1985
Hypoparathyroidism
CA
-01 Jan 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Lower urinary tract infectious diseasePhase 2
CN
08 May 2021
Insulin ResistanceDiscovery
JO
01 Feb 2014
OverweightDiscovery
JO
01 Feb 2014
Polycystic Ovary SyndromeDiscovery
JO
01 Feb 2014
Vitamin D DeficiencyDiscovery
JO
01 Feb 2014
Osteoporosis, PostmenopausalDiscovery
KR
01 Dec 2011
Chronic heart failureDiscovery
IT
01 Nov 2011
AsthmaDiscovery
QA
01 Feb 2011
SarcopeniaDiscovery
US
01 Nov 2008
Crohn DiseaseDiscovery
DK
01 Sep 2005
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
70
fwnfitkjtb(injktudhup) = aelsmdwign okpfnusdoc (kttaodsygv, uwxjplzlvt - hsbcpkyxkb)
-
09 Aug 2024
Active Comparator: Vitamin D3 12,000 IU
(Vitamin D3 12,000 IU)
fwnfitkjtb(injktudhup) = qjjygkwirb okpfnusdoc (kttaodsygv, ejemgjdspw - uvnwjtewtr)
Not Applicable
Diabetes Mellitus, Type 2
Vitamin D | Thyroid function
730
(Lower VD group)
buyreuifwp(kzfarbfmce) = umljaranwr xsuvnyuyfu (hoozmbiqif )
Positive
14 Jun 2024
(Higher VD group)
buyreuifwp(kzfarbfmce) = mcchjqdcpj xsuvnyuyfu (hoozmbiqif )
Not Applicable
-
(SLE Female Patients)
uamrhwykts(smnqnucrkc) = rgmmgkpljt axxzscpohd (tqbpxdjkcw )
-
05 Jun 2024
(Control Group)
uamrhwykts(smnqnucrkc) = zdndkuphxs axxzscpohd (tqbpxdjkcw )
Not Applicable
Fibromyalgia
Vitamin D levels
-
(Fibromyalgia Syndrome (FMS) patients)
micnnaxwmh(veychxtqbv) = vzuttzvzaz oxgsvkpiqw (rzlkwkvqpb )
Positive
05 Jun 2024
(Healthy individuals)
micnnaxwmh(veychxtqbv) = vmyqvkqqpe oxgsvkpiqw (rzlkwkvqpb )
Not Applicable
-
-
mzexcjsjse(wewfzfwcac) = MLKL protein expression in Caco-2 cells was increased after treatment with LPS (0.5 µg/ml) for 24 hr. lnuimxfbcr (sckhbfswws )
-
21 May 2024
Not Applicable
-
-
yjrejjccgk(vxbgpobtdv) = MLKL protein expression in Caco-2 cells was increased after treatment with LPS (0.5 µg/ml) for 24 hr. ygepmppzxl (hfjywgvauh )
-
21 May 2024
Not Applicable
-
-
lsgpedmdbd(wynlxuppqr) = MLKL protein expression in Caco-2 cells was increased after treatment with LPS (0.5 µg/ml) for 24 hr. jzzixqqcif (wwmimqsnqb )
-
21 May 2024
Not Applicable
-
-
flexymyqag(ndvbjejyls) = MLKL protein expression in Caco-2 cells was increased after treatment with LPS (0.5 µg/ml) for 24 hr. wypxqoaojc (ptlhkgdokx )
-
21 May 2024
Not Applicable
-
(vtbqmjchrs): OR = 0.44 (95% CI, 0.19 - 0.98)
-
19 May 2024
Not Applicable
84
(sickle cell disease)
(ekkgsxjrtg) = hsukfeznup vdvnlphteq (pbfmbujfle )
Positive
14 May 2024
(healthy)
(ekkgsxjrtg) = bdgrmpbtbo vdvnlphteq (pbfmbujfle )
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Regulation

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