Drug Type Small molecule drug |
Synonyms OPB 31121 |
Target |
Mechanism STAT3 inhibitors(Signal transducer and activator of transcription 3 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hepatocellular Carcinoma | Phase 2 | JP | 01 Jul 2011 | |
Liver Cancer | Phase 2 | - | - | |
Advanced cancer | Phase 1 | US | 01 Jun 2009 | |
Acute Lymphoblastic Leukemia | Phase 1 | US | 01 Jul 2008 | |
Acute Myeloid Leukemia | Phase 1 | US | 01 Jul 2008 | |
Chronic Lymphocytic Leukemia | Phase 1 | US | 01 Jul 2008 | |
Myelodysplastic Syndromes | Phase 1 | US | 01 Jul 2008 | |
Philadelphia chromosome positive chronic myelogenous leukemia | Phase 1 | US | 01 Jul 2008 | |
Refractory Leukemia | Phase 1 | US | 01 Jul 2008 | |
Advanced Malignant Solid Neoplasm | Phase 1 | KR | 01 Mar 2008 |
Phase 1 | 23 | rjbpnmidji(mtrebrdokj) = tdjwlmmbnh swnjoisnuk (njqfaqylgb ) View more | Negative | 01 Dec 2015 | |||
Phase 1 | 25 | jaijdomxet(sovidldxcf) = wtrtiovdba fecgyxwfsj (rvyuftvwyc ) View more | Positive | 01 Oct 2015 | |||
Phase 1/2 | 23 | (OPB-31121) | mjzmiyeufg(snznauygcw) = euucyolwhe tmcjapmkwv (ppsigkfbri, eoezhrapuv - onevxrxjid) View more | - | 08 Jun 2015 | ||
(OPB-31121: 50 mg/Day) | zexmgpwhhe(wezklyewgs) = mihmgojycx cojmevebed (wozbvjnvii, gvsadkxpir - wtnntinods) View more | ||||||
Phase 1 | 30 | ivauqjfdcw(okzkibqdyk) = aeyiwatykc nejavsteuu (vqrdiuneoo ) View more | Negative | 01 Jul 2014 | |||
Phase 1 | 23 | lnmwkjlwkl(lxhumeisvg) = racfiozpak afvfcsvlrc (onzydpnckq ) | - | 20 May 2014 | |||
lnmwkjlwkl(lxhumeisvg) = oyljgfxakh afvfcsvlrc (onzydpnckq ) |