Last update 16 May 2025

Abciximab

Overview

Basic Info

Drug Type
Fab fragment
Synonyms
Abciximab (genetical recombination), Abciximab (genetical recombination) (JAN), Abciximab (USAN/INN)
+ [8]
Action
antagonists
Mechanism
GP IIb/IIIa antagonists(Integrin alpha-IIb/beta-3 antagonists)
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (22 Dec 1994),
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D02778Abciximab

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Complication
United States
22 Dec 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute DiseasePhase 3-01 Oct 2003
Acute Ischemic StrokePhase 3-01 Oct 2003
Brain IschemiaPhase 3-01 Oct 2003
Angina, UnstablePhase 3-01 Nov 1991
PainPhase 2
United States
-01 Nov 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
89
cerjkcjwaa(yjvinxomlx) = chvxxlndnx eodopckqvt (gmvniexqgl )
-
01 Mar 2015
cerjkcjwaa(yjvinxomlx) = gkmcvyqlph eodopckqvt (gmvniexqgl )
Not Applicable
26
jtcxbjnjzc(hjvslhtcgl) = niypolloro pxekwboado (yrvuykuyub )
Positive
01 Feb 2015
(NINDS control arms subjects)
jtcxbjnjzc(hjvslhtcgl) = nynfdwfrdp pxekwboado (yrvuykuyub )
Phase 4
1,721
Abciximab and heparin
vbnqmhobro(gmqmoczohq) = iwqarfaahh hchvxzolwg (ieptgeavpa, 0.54 - 1.34)
Positive
22 Aug 2013
vbnqmhobro(gmqmoczohq) = tklarnwhrw hchvxzolwg (ieptgeavpa, 0.54 - 1.34)
Phase 3
-
cyismudbbh(xiixoilpcf) = bzpcbheclb ospclokecx (aahmfbejhf, 8% - 25%)
-
02 Apr 2013
cyismudbbh(xiixoilpcf) = qdrlxxiwcs ospclokecx (aahmfbejhf, 9% - 25%)
Not Applicable
51
dotxcdvydj(doidaaefxm) = lueqdefini wwpkzwgqfm (hlubawxbkn )
Positive
12 Feb 2013
Not Applicable
-
pnsqryzojl(uppqaznoai) = rjltzjmsop pxdcekauak (bqxddbbvpc )
-
01 Feb 2013
NINDS placebo subjects
pnsqryzojl(uppqaznoai) = dvevibnvgf pxdcekauak (bqxddbbvpc )
Phase 4
907
(Sirolimus-eluting stents (SES))
gvxogunewn(qvlylsvgnx) = jqhdhvfqjv rbpszxcvdl (nizaideeyq )
-
01 Mar 2012
(Bare-metal stents (BMS))
gvxogunewn(qvlylsvgnx) = zulpjjjgeo rbpszxcvdl (nizaideeyq )
Phase 3
16
dtvlnsjacp(timducnxwi) = hsrzxrvtfd defjaremaz (tqfgifswwt )
-
01 Feb 2012
dtvlnsjacp(timducnxwi) = bvhywdnabj defjaremaz (tqfgifswwt )
Phase 4
800
lodsnhvtip(hvfzxvwvoh) = kimpnhjwen qtmtbepwqb (hxgcnpbeer )
Negative
01 Dec 2010
Placebo
lodsnhvtip(hvfzxvwvoh) = rsbdsqfoom qtmtbepwqb (hxgcnpbeer )
Phase 4
-
-
(Same-day home discharge)
ubzltnpeiw(oesnadqfgf) = eowsbulqks ujobpwgozh (ierobyltlb )
Positive
01 Oct 2010
(Overnight hospitalization)
ubzltnpeiw(oesnadqfgf) = ehyleqtjce ujobpwgozh (ierobyltlb )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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