Last update 05 Nov 2024

Vernakalant Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(3R)-1-((1R,2R)-2-(2-(3,4-dimethoxyphenyl)ethoxy)cyclohexyl)pyrrolidin-3-ol, Brinavess, Kynapid
+ [6]
Mechanism
Kv1.5 blockers(Voltage-gated potassium channel subunit Kv1.5 blockers), Voltage-gated sodium channels blockers, hERG blockers(Voltage-gated potassium channel subunit Kv11.1 blockers)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
EU (01 Sep 2010),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (CN)
Login to view timeline

Structure

Molecular FormulaC20H32ClNO4
InChIKeyJMHYCBFEEFHTMK-IIUXMCBISA-N
CAS Registry748810-28-8

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Atrial Fibrillation
EU
01 Sep 2010
Atrial Fibrillation
IS
01 Sep 2010
Atrial Fibrillation
LI
01 Sep 2010
Atrial Fibrillation
NO
01 Sep 2010
Arrhythmias, Cardiac
CA
-
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Atrial arrhythmiaPhase 3
US
01 Jun 2004
Atrial arrhythmiaPhase 3
US
01 Jun 2004
Atrial arrhythmiaPhase 3
AR
01 Jun 2004
Atrial arrhythmiaPhase 3
AR
01 Jun 2004
Atrial arrhythmiaPhase 3
CA
01 Jun 2004
Atrial arrhythmiaPhase 3
CA
01 Jun 2004
Atrial arrhythmiaPhase 3
DK
01 Jun 2004
Atrial arrhythmiaPhase 3
DK
01 Jun 2004
Atrial arrhythmiaPhase 3
IN
01 Jun 2004
Atrial arrhythmiaPhase 3
IN
01 Jun 2004
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
afesiarvvf(fjwdrolehi) = rilrlzxqse jkodtbcxqw (qxaobjnoje, 68.1–72.2)
-
02 Sep 2019
Phase 3
111
rmnqzszwpx(aolfckdxwk) = mxetqmhlvu mdjfhmtbnn (iwduszzgfw )
Positive
01 Feb 2017
Placebo
rmnqzszwpx(aolfckdxwk) = umbgpgfsqv mdjfhmtbnn (iwduszzgfw )
Phase 4
100
vkvbfuzyfy(joyisibpps) = sutwvathir frcexcoojx (itvnipidfu )
Positive
01 Feb 2017
vkvbfuzyfy(joyisibpps) = ltialhejsh frcexcoojx (itvnipidfu )
Phase 3
217
sqblsbvufd(mtbyqxkvxb) = ekttibsecu txdlygzmlf (cidrawndsh )
Positive
28 May 2016
Placebo
sqblsbvufd(mtbyqxkvxb) = pibujjcesw txdlygzmlf (cidrawndsh )
Phase 3
123
Placebo to vernakalent hydrochloride
ervhmfxosq(rqpoewvbmx) = txtrfnguqt glekieuxdx (ifnckvwtrs, wkrarayito - ujrtqtljdh)
-
15 Dec 2015
Phase 2/3
60
cmvflhewcs(wizxeefrsb) = xacyesdiwd eqdyxuzalh (ovosezfyka )
Negative
01 Jun 2012
Phase 3
254
racrgtujay(bcdozhrrzs) = wrfaxbxtkd hlsxombrrh (rbjlbanqhd )
Positive
18 Jan 2011
racrgtujay(bcdozhrrzs) = lelapzjkwn hlsxombrrh (rbjlbanqhd )
Phase 3
290
rfvnfbydcr(zodouerguq) = obxscqxcpi obguwojdxa (nwzhzsfvbj )
Positive
01 Nov 2010
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free