Last update 04 Nov 2024

Drospirenone/Estetrol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Estetrol Hydrate/Drospirenone, Estetrol/Drospirenone, PeriNesta
+ [10]
Mechanism
AR antagonists(Androgen Receptor antagonists), ERs modulators(Estrogen receptors modulators), MR antagonists(Mineralocorticoid receptor antagonists)
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (28 Sep 2005),
Regulation-
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Structure

Molecular FormulaC18H24O4
InChIKeyAJIPIJNNOJSSQC-NYLIRDPKSA-N
CAS Registry15183-37-6
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
-Drospirenone/Estetrol-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dysmenorrhea
JP
24 Sep 2024
Contraception
US
15 Apr 2021
Hot Flashes
US
28 Sep 2005
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Vasomotor symptomPhase 2
BE
01 May 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
89
wwvogzjngm(opkoouwvgi) = no new safety signals were observed. bfletkjgew (qzbbiihtyr )
Positive
17 Apr 2024
Phase 3
2,148
blgasulbfo(yepudoogtj) = jjdkaopcud rhctrizpyb (xhvsagizlo, nvirjdvllm - bnbaoeeryw)
-
06 Nov 2019
Phase 3
1,577
tbfhrkvkkx(qhqbwkeiwk) = xjejegftxu hqgaxwjvxt (jickglhaub, nkbakylqts - udkokmujnk)
-
04 Oct 2019
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Regulation

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