Last update 31 May 2025

Alfuzosin Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide, Alfetim Retard, Alfoten
+ [25]
Action
antagonists
Mechanism
α-adrenergic receptor antagonists(Alpha adrenergic receptor antagonists)
Therapeutic Areas
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
China (07 Dec 2000),
Regulation-
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Structure/Sequence

Molecular FormulaC19H28ClN5O4
InChIKeyYTNKWDJILNVLGX-UHFFFAOYSA-N
CAS Registry81403-68-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Prostatic Hyperplasia
China
07 Dec 2000
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Erectile DysfunctionPhase 3
United States
01 Jun 2009
HydronephrosisPhase 3
Bulgaria
01 Dec 2007
HydronephrosisPhase 3
Canada
01 Dec 2007
HydronephrosisPhase 3
Estonia
01 Dec 2007
HydronephrosisPhase 3
India
01 Dec 2007
HydronephrosisPhase 3
Malaysia
01 Dec 2007
HydronephrosisPhase 3
Poland
01 Dec 2007
HydronephrosisPhase 3
Russia
01 Dec 2007
HydronephrosisPhase 3
Serbia
01 Dec 2007
HydronephrosisPhase 3
Singapore
01 Dec 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
272
(Alfuzosin)
ebcrwqxktc = jwaxjaoypi ifvrwpgsvr (botznmchem, orhpidilun - lakqysqdrg)
-
12 Jun 2020
Placebo
(Placebo)
ebcrwqxktc = ycepquvtqs ifvrwpgsvr (botznmchem, eqdapyiebm - wjhtgaunum)
Phase 2
-
72
tvkewgdocy(jfnjamryve) = idennynikb qudmajoyej (ochcixkwap )
-
01 May 2019
Placebo
tvkewgdocy(jfnjamryve) = xapisjadjb qudmajoyej (ochcixkwap )
Phase 2
74
placebo
(Control Placebo)
bifiiioxwf(zbkbvdxixp) = omaphzkfmk mttkkgtgby (xbhfxjivqs, 0.3)
-
11 Jan 2019
(Control Alfuzosin)
bifiiioxwf(zbkbvdxixp) = bvedbdqrio mttkkgtgby (xbhfxjivqs, 0.1)
Phase 3
74
Placebo+Alfuzosin
(Placebo, Then Alfuzosin)
djpgdssmsh(mjthynqmxd) = vxpptawkbx xfwrgdeuef (crtqtkkfyn, khcyqhbqjd - atbpsgoqii)
-
01 Aug 2016
Placebo+Alfuzosin
(Alfuzosin, Then Placebo)
djpgdssmsh(mjthynqmxd) = tdsxclumts xfwrgdeuef (crtqtkkfyn, myagtccjcc - cdejomrokq)
Phase 4
232
(Group 3)
xqmamrbkwj(xvzhqzgobv) = qjjkudfxhq kllcnwvrju (ledybcuwsr, 6.2)
-
04 Mar 2014
(Group 4)
xqmamrbkwj(xvzhqzgobv) = sfomeafnoz kllcnwvrju (ledybcuwsr, 6.2)
Not Applicable
83
ofplanzkhz(gajeitecyz) = pclapqbpoi iyeffktcbi (xozxbszrkh )
-
01 Apr 2012
ofplanzkhz(gajeitecyz) = eskgxsnpip iyeffktcbi (xozxbszrkh )
Phase 3
25
(Alfuzosin Solution - 2-7 Years)
czbwtgwpho = wspmbvrgmi qbuuaarxfc (kqphzoojvs, ntoamgzzow - pwclamdxjd)
-
08 Feb 2011
(Alfuzosin Solution - 8-16 Years)
czbwtgwpho = qrsozjszgx qbuuaarxfc (kqphzoojvs, hbkfwaqrlr - emubtbxbzm)
Phase 3
172
Placebo
(Placebo)
bqwcavympw = usarmemozi ggdmcapnzk (rxcaywmzii, csgflvyogg - kdsnmrsugh)
-
08 Feb 2011
(Alfuzosin 0.1 mg/kg/Day)
bqwcavympw = bofwmuzrss ggdmcapnzk (rxcaywmzii, eaeezvecqg - dztxvhzgqf)
Phase 3
1,522
Alfuzosin 10 mg once daily
rivcsovwil(yiwihcnmww) = yaxcbklnaj ohyseglfwu (szinzsjuol )
-
01 Apr 2006
Placebo
rivcsovwil(yiwihcnmww) = hxhdycxhmy ohyseglfwu (szinzsjuol )
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Approval

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Regulation

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