Last update 23 Mar 2025

Resiniferatoxin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lopain, RTX, MTX-071
+ [1]
Target
Action
agonists
Mechanism
TRPV1 agonists(Vanilloid receptor agonists)
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (United States), Breakthrough Therapy (United States)
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Structure/Sequence

Molecular FormulaC37H40O9
InChIKeyDSDNAKHZNJAGHN-MXTYGGKSSA-N
CAS Registry57444-62-9

External Link

KEGGWikiATCDrug Bank
-Resiniferatoxin-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PainPhase 3
Japan
26 Aug 2022
PainPhase 3
Canada
26 Aug 2022
PainPhase 3
Czechia
26 Aug 2022
PainPhase 3
France
26 Aug 2022
PainPhase 3
Germany
26 Aug 2022
PainPhase 3
Italy
26 Aug 2022
PainPhase 3
Mexico
26 Aug 2022
PainPhase 3
Netherlands
26 Aug 2022
PainPhase 3
Poland
26 Aug 2022
Arthritis PainPhase 3
United States
30 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
67
RTX-GRT7039 0.5 mg
hlcyfarfkh(ropfnpxtpx) = ozanzpvtrc fcxbzlucyb (ieojoxywmn, 19.79)
Positive
14 Jun 2024
hlcyfarfkh(ropfnpxtpx) = hvusznwsmj fcxbzlucyb (ieojoxywmn, 34.16)
Not Applicable
62
ragemdxrhw(xqkhjswvgs) = xizqmebmcw rhocnklmlh (bkaagjsidz )
Positive
27 Oct 2021
ragemdxrhw(xqkhjswvgs) = dstqmkoqvl rhocnklmlh (bkaagjsidz )
Not Applicable
107
nfqfxnwhzv(matmzbefbt) = Hypogammaglobulinemia is a frequent complication of RTX treatment in younger children treated for SDNS. The use of RTX in children younger than 8 years has to be carefully evaluated and their clinical and biological follow up should be adapted to the increased risk profil for hypogammaglobulinemia rbjdqdczqf (baeiwxnptu )
Negative
13 Jun 2019
Not Applicable
-
Resiniferatoxin (RTX)
nsakylrlld(rqhjtolkkm) = aadcbnbuhn xgdlnmkfjc (wxflccnjhg )
-
24 Oct 2004
Vehicle
nsakylrlld(rqhjtolkkm) = jygegiiulb xgdlnmkfjc (wxflccnjhg )
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Regulation

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