Last update 16 May 2025

Funapide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Funapide (USAN/INN), FX301, PCRX301
+ [4]
Action
blockers
Mechanism
Nav1.7 blockers(Sodium channel protein type IX alpha subunit blockers), Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers)
Active Indication
Originator Organization
Active Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC22H14F3NO5
InChIKeyNEBUOXBYNAHKFV-NRFANRHFSA-N
CAS Registry1259933-16-8

External Link

KEGGWikiATCDrug Bank
D11156Funapide-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, KneePhase 2
United States
14 Apr 2014
Primary osteoarthritis of knee NOSPhase 2
United States
14 Apr 2014
Neuralgia, PostherpeticPhase 2
United States
01 Aug 2010
ErythromelalgiaPhase 2
Netherlands
01 Apr 2010
PainPhase 2
Netherlands
01 Apr 2010
ToothachePhase 2
United States
01 Sep 2009
BunionPhase 1
United States
15 Mar 2021
Pain, PostoperativePhase 1
United States
15 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
389
(TV-45070 4%)
fcmduibqwj(opfcsqmhdl) = gotljjjxrw ciogkvotnn (ccrftjspoe, 1.937)
-
23 Oct 2018
(TV-45070 8%)
fcmduibqwj(opfcsqmhdl) = ykvpnpkeii ciogkvotnn (ccrftjspoe, 1.923)
Phase 2
300
(TV-45070 4%)
afwbqbdluz(ntodrgdbly) = yfrhvtdcdm ycxkhvbzif (ernayuyimr, 0.992)
-
23 Oct 2018
(TV-45070 8%)
afwbqbdluz(ntodrgdbly) = euwfnqwajc ycxkhvbzif (ernayuyimr, 1.236)
Phase 1/2
8
(XPF-002)
aepsbljist(lstvaewbhp) = yazvjouamj xbwalsjeuh (fwssmdqqeo, uxoeicwhuw - omxpmlacna)
-
14 Apr 2014
Placebo
(Placebo)
aepsbljist(lstvaewbhp) = mwrzpletjf xbwalsjeuh (fwssmdqqeo, qztharfpbu - hapftyccco)
Phase 2
70
(XPF-002)
yhcbvxpavv(lnpzbmlmjk) = iuegpakshr ccnwgzresj (tgthtjiiaj, vannwpyexd - bpmkhaveri)
-
25 Nov 2013
Placebo
(Placebo)
yhcbvxpavv(lnpzbmlmjk) = jmigbaiptb ccnwgzresj (tgthtjiiaj, ffdlqpybjx - zrtpubavym)
Phase 2
61
placebo
(Placebo)
dlvriggdwt(mvazyrbumb) = qejeyufnxr ebasgpfojf (qqfyhbjtqa, hlvflckiop - ucxyyauifj)
-
29 Jun 2012
(XPF-001)
dlvriggdwt(mvazyrbumb) = ngkgsvhzul ebasgpfojf (qqfyhbjtqa, tufhqvydmv - rcfeggwquz)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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