Last update 30 Jun 2024

AVID-100

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
AVID 100
Target
EGFR
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Breast CancerSquamous Cell Carcinoma
Inactive Indication
Non-Small Cell Lung CancerSquamous Cell Carcinoma of Head and NeckTriple Negative Breast Cancer
Originator Organization
Bristol-Myers Squibb FCT bêta, Inc.
Active Organization
Bristol-Myers Squibb FCT bêta, Inc.
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

Structure

Molecular FormulaC35H48ClN3O10S
InChIKeyANZJBCHSOXCCRQ-FKUXLPTCSA-N
CAS Registry139504-50-0
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Related

1
Clinical Trials associated with AVID-100
NCT03094169 / TerminatedPhase 1/2
Phase 1a/2a Dose Escalation Trial to Determine Safety, Tolerance, MTD, and Preliminary Antineoplastic Activity of AVID100, in Patients With Advanced or Metastatic Solid Tumors of Epithelial Origin
100 Clinical Results associated with AVID-100
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100 Translational Medicine associated with AVID-100
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100 Patents (Medical) associated with AVID-100
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100 Deals associated with AVID-100
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Squamous Cell CarcinomaPhase 2
US
-06 Sep 2019
Breast CancerPhase 2
US
-12 Apr 2019
Non-Small Cell Lung CancerPhase 2
US
Bristol-Myers Squibb FCT bêta, Inc.
01 Feb 2017
Squamous Cell Carcinoma of Head and NeckPhase 2
US
Bristol-Myers Squibb FCT bêta, Inc.
01 Feb 2017
Triple Negative Breast CancerPhase 2
US
Bristol-Myers Squibb FCT bêta, Inc.
01 Feb 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03094169 (AACR2019)
ManualManual
Phase 1/2
Carcinoma
EGFR Overexpression | ER Negative | PR Negative ...
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-
oeawxhfkie(hgehqrkjyk) = G3 asymptomatic lipase elevation, G4 reversible thrombocytopenia flwnfoyspr (gtabvoduqm )
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Positive
01 Jul 2019
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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