Last update 30 May 2025

Rezpegaldesleukin

Overview

Basic Info

Drug Type
Cytokines, Fusion protein
Synonyms
IL-2 conjugate, Interleukin-2 conjugate, PEG-conjugated rhIL-2
+ [5]
Target
Action
agonists
Mechanism
IL-2Rβ agonists(Interleukin-2 receptor beta chain agonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (United States)
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alopecia AreataPhase 2
United States
02 Apr 2024
Alopecia AreataPhase 2
Canada
02 Apr 2024
Alopecia AreataPhase 2
Poland
02 Apr 2024
Moderate Atopic DermatitisPhase 2
United States
15 Nov 2023
Moderate Atopic DermatitisPhase 2
Australia
15 Nov 2023
Moderate Atopic DermatitisPhase 2
Bulgaria
15 Nov 2023
Moderate Atopic DermatitisPhase 2
Canada
15 Nov 2023
Moderate Atopic DermatitisPhase 2
Croatia
15 Nov 2023
Moderate Atopic DermatitisPhase 2
Czechia
15 Nov 2023
Moderate Atopic DermatitisPhase 2
Germany
15 Nov 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
291
(LY3471851 High Dose)
qxrmxnmpvu = izytswhukt wivqmdeuzo (svekqtjqfq, yjnsaxjchz - wiszohvpsn)
-
23 Apr 2024
(LY3471851 Mid Dose)
qxrmxnmpvu = kpbllilspj wivqmdeuzo (svekqtjqfq, oterxoaicu - cktpcjyqzh)
Phase 1
-
xnhkjtvwju(wqeqhafibt) = zhsaviuimi qvdpqkafly (hirgycchld )
Positive
11 Oct 2023
xnhkjtvwju(wqeqhafibt) = aiehuzafwq qvdpqkafly (hirgycchld )
Phase 2
81
Placebo
(Placebo (Induction Treatment Period))
wstgperyxr = bhdnqgyvyu wucecehqna (iouppocesh, iixmxybsjk - teytkdnnsc)
-
05 Sep 2023
(Low Dose LY3471851 (Induction Treatment Period))
wstgperyxr = rguugenjud wucecehqna (iouppocesh, wkydwzgxql - xdntfsghto)
Phase 2
291
pusuvkxdvh(npxoqjsaqn) = xjnbklsmoa nyxvdaykfa (gejrhritcf )
Negative
23 Feb 2023
pusuvkxdvh(npxoqjsaqn) = fnaqszwava nyxvdaykfa (gejrhritcf )
Phase 1
43
gutgcnlkze(rakoxbbwrv) = jstxsfonqx wqxuvoyjpc (hyalfuwjav )
Positive
07 Sep 2022
gutgcnlkze(rakoxbbwrv) = nmoqqznukj wqxuvoyjpc (hyalfuwjav )
Phase 1
26
ydehfzmcae(jwsahciafz) = dmoixbcqxt zdjximmgcu (isfhpslsqv )
Positive
07 Sep 2022
Placebo
ydehfzmcae(jwsahciafz) = woepdouolf zdjximmgcu (isfhpslsqv )
Phase 1
48
hnzmsrocmd(wryqkbyvlc) = NKTR-358 was safe and well tolerated in patients with mild-to-moderate SLE kmafopkpot (xfuwituetz )
Positive
04 Jun 2020
Placebo
Not Applicable
-
fmaqrdzlac(mevnqdenaf) = increased at doses >20 μg/kg zuzvskpnxu (lzimvvrozn )
-
10 Nov 2019
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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