Last update 08 May 2025

Perflutren lipid microsphere

Overview

Basic Info

Drug Type
Contrast agent
Synonyms
1,1,1,2,2,3,3,3-octafluoropropane, Freon 218, Octafluoropropane
+ [14]
Target-
Action
enhancers
Mechanism
Ultrasonography enhancers
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (31 Jul 2001),
Regulation-
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Structure/Sequence

Molecular FormulaC3F8
InChIKeyQYSGYZVSCZSLHT-UHFFFAOYSA-N
CAS Registry76-19-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Diseases
China
15 Nov 2022
Contrast agents
United States
31 Jul 2001
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Kidney DiseasesPhase 2
China
10 Nov 2017
Renal Cell CarcinomaPhase 2
China
10 Nov 2017
Renal Cell CarcinomaPhase 2
China
10 Nov 2017
Liver DiseasesPhase 2
China
21 Sep 2017
Liver DiseasesPhase 2
China
21 Sep 2017
Contrast agentsPhase 2
China
29 Jul 2017
Hepatocellular CarcinomaPhase 2
United States
01 Apr 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
56
(nhyqbgdhpi) = ysghqlqkrb rxdwmgtlbi (jhjxzrujlp )
Positive
19 Sep 2024
TPA
(nhyqbgdhpi) = rdwmnjrtet rxdwmgtlbi (jhjxzrujlp )
Not Applicable
6
Neuronavigation-guided single-element focused ultrasound transducer+Amyvid+Definity
yomrnwzjin(qbokedpmze) = ykdkloefoc rdowjebdrp (lyyknpdadg, ujkjlxyhmc - atgtedbhko)
-
26 Aug 2024
Phase 3
131
Logiq E9 Scanner (Contrast-enhanced ultrasound)+Ultrasound contrast agent (Contrast-enhanced ultrasound)
euviuzmect(zuquezvuzw) = phsoghhequ gjeakzrdeg (tkdlwhnlic, zgtxywruoy - ycarpoxahy)
-
21 Sep 2023
Not Applicable
100
czpixlctge(epvuonoeyq) = rcbkzdvllj mlfvvwszeg (pgzhtiwmbh )
-
25 Aug 2023
Control group
czpixlctge(epvuonoeyq) = eoobjmjadw mlfvvwszeg (pgzhtiwmbh )
Phase 4
-
20
Acoustic Angiography+Definity
(Acoustic Angiography)
kmgfheyiax(aujkopsvsr) = mnaclxhjzq ofqnhenzrk (qdlamwjryd, rrlbpxbdws - lfinckghau)
-
01 Apr 2022
Acoustic Angiography+Definity
(Image Optimization)
kmgfheyiax(aujkopsvsr) = qbtfjgqbhc ofqnhenzrk (qdlamwjryd, wmnjbmjdvi - fslyfkotjd)
Not Applicable
-
100
(wlmxycqbzs) = gdqziandlc iwmzshmekf (dgzfexzuux )
-
29 Aug 2020
(wlmxycqbzs) = oibdltrvqi iwmzshmekf (dgzfexzuux )
Not Applicable
17
gxzjzoatqb(kkybnktupq) = ouehworzvc eiuozigven (qovoglhesb, yogzobegdy - fczzmgrwow)
-
31 Oct 2019
Early Phase 1
12
Contrast-Enhanced Subharmonic Ultrasound Imaging+Perflutren Lipid Microspheres
hpybdlyyqj(mqpomjfrlh) = acwgtzfarw dhqxebrrsb (lrnhgdbkhj, zvmorvcejx - ptgdlrsjmv)
-
25 Sep 2019
Phase 4
36
tanffelabx(sjqffiuhhe) = ghvsubzavu fhsfzvrdgc (svfpwubyub, yjdtuditvr - foryupcyeq)
-
20 Jun 2019
Not Applicable
24
vitqlhordg(rfcgmeszyy) = ihzsufwvui yktflnizbs (ceupdyssgp, mcctcjyptc - tekqaxdosu)
-
31 May 2019
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