Last update 05 Nov 2024

AEG-35156

Overview

Basic Info

Drug Type
ASO
Synonyms
AEG 161, AEG 35156, AEG-161
+ [3]
Target
Mechanism
XIAP inhibitors(Inhibitor of apoptosis protein 3 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 2
US
01 Nov 2009
Acute Myeloid LeukemiaPhase 2
CA
01 Nov 2009
Acute Myeloid LeukemiaPhase 2
DE
01 Nov 2009
Hepatocellular CarcinomaPhase 2
CN
31 Mar 2009
Advanced Hepatocellular CarcinomaPhase 2
CN
01 Mar 2009
B-Cell LeukemiaPhase 2
US
01 Sep 2008
B-Cell LeukemiaPhase 2
CA
01 Sep 2008
B-Cell LymphomaPhase 2
US
01 Sep 2008
B-Cell LymphomaPhase 2
CA
01 Sep 2008
Chronic Lymphocytic LeukemiaPhase 2
CA
31 Jul 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
51
gscrswdmez(yauqhfdgnz) = yzkenyrgyi qjjzbtisls (eedelewmti, 1.2 - 4.1)
Positive
01 Dec 2016
gscrswdmez(yauqhfdgnz) = zjvctasuwl qjjzbtisls (eedelewmti, 1.2 - 5.4)
Phase 1
-
iccyujobiy(oxilzwyjli) = Three DLTs were observed at AEG35156 350mg: Grade 3 chills/lethargy (mesothelioma), grade 3 transaminitis (colon), transient grade 3 chills/tumour lysis syndrome/transaminitis (small lymphocytic lymphoma) gqrrgsbuha (wlfcnftdur )
-
20 May 2008
Phase 1
16
freqoflkku(eqzdyiciqk) = pewppptjcu cvxkeaslbi (llkjpyxlbz )
-
20 Jun 2006
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Regulation

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