Drug Type ASO |
Synonyms AEG 161, AEG 35156, AEG-161 + [3] |
Target |
Mechanism XIAP inhibitors(Inhibitor of apoptosis protein 3 inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Myeloid Leukemia | Phase 2 | US | 01 Nov 2009 | |
Acute Myeloid Leukemia | Phase 2 | CA | 01 Nov 2009 | |
Acute Myeloid Leukemia | Phase 2 | DE | 01 Nov 2009 | |
Hepatocellular Carcinoma | Phase 2 | CN | 31 Mar 2009 | |
Advanced Hepatocellular Carcinoma | Phase 2 | CN | 01 Mar 2009 | |
B-Cell Leukemia | Phase 2 | US | 01 Sep 2008 | |
B-Cell Leukemia | Phase 2 | CA | 01 Sep 2008 | |
B-Cell Lymphoma | Phase 2 | US | 01 Sep 2008 | |
B-Cell Lymphoma | Phase 2 | CA | 01 Sep 2008 | |
Chronic Lymphocytic Leukemia | Phase 2 | CA | 31 Jul 2008 |
NCT00882869 (Pubmed) Manual | Phase 2 | 51 | gscrswdmez(yauqhfdgnz) = yzkenyrgyi qjjzbtisls (eedelewmti, 1.2 - 4.1) View more | Positive | 01 Dec 2016 | ||
gscrswdmez(yauqhfdgnz) = zjvctasuwl qjjzbtisls (eedelewmti, 1.2 - 5.4) View more | |||||||
Phase 1 | - | iccyujobiy(oxilzwyjli) = Three DLTs were observed at AEG35156 350mg: Grade 3 chills/lethargy (mesothelioma), grade 3 transaminitis (colon), transient grade 3 chills/tumour lysis syndrome/transaminitis (small lymphocytic lymphoma) gqrrgsbuha (wlfcnftdur ) View more | - | 20 May 2008 | |||
Phase 1 | 16 | freqoflkku(eqzdyiciqk) = pewppptjcu cvxkeaslbi (llkjpyxlbz ) | - | 20 Jun 2006 |