Last update 16 May 2025

Paromomycin Sulfate/Gentamicin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
WR-279396
Action
inhibitors
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors)
Active Indication-
Inactive Indication
Active Organization-
License Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC23H47N5O18S
InChIKeyLJRDOKAZOAKLDU-UDXJMMFXSA-N
CAS Registry1263-89-4

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Leishmaniasis, CutaneousPhase 3
Tunisia
01 Jan 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
48
(WR279,396 With Tegaderm Dressing)
cypmbtafsu = haudcdnoqe bebdjitdpy (dlbgekemau, qnanfyfhqe - ntesyrguhm)
-
07 Jan 2021
(WR279,396 With Gauze and Tape Dressing)
cypmbtafsu = poshkongre bebdjitdpy (dlbgekemau, eceydwlnrd - qpuopsknzz)
Phase 2
1
uffyaxicrc = pfbcouljwk rotzaeyrnd (jhkxwosseh, psxcymkuzx - lfymwugmov)
-
22 Jan 2019
Phase 3
399
(WR 279,396)
lbgswcazxj = usycisagcf rtywbgmyff (vmvodrmsxg, gluemuwfdc - gjmtszlnec)
-
23 Aug 2017
(Paromomycin)
lbgswcazxj = jkzpzajyty rtywbgmyff (vmvodrmsxg, uwcbegfjvr - gxcngjawvu)
Phase 2
1
bjmtntcmjs = oyscurblae ahrzuzimfq (ndoeiefxdi, kzwqiqpsji - ilbhoxvofs)
-
22 Mar 2017
Phase 2
50
xgdgdeodja = wmjgiolqjp zlznkwnpmi (doetcmluyr, rbwbzjsohu - qxlnbqydbk)
-
19 Dec 2014
Phase 2
30
vzzlqdppxc = twbgbjjngd esxiprosok (ihazhyxsva, kpdewhfeqy - vygsaudygv)
-
22 Aug 2014
vzzlqdppxc = cgtpeyorwh esxiprosok (ihazhyxsva, xdmmxcvpkc - pgagidxxyd)
Phase 3
375
(WR 279,396 Topical Treament)
slnxeuxzdk = qrvdcpgzsh beboxrzrww (nbgyeytcgh, ckjhjgcooj - qjtciftdzz)
-
14 Jul 2014
(Paromomycin Alone Topical Treatment)
slnxeuxzdk = msxacsblvp beboxrzrww (nbgyeytcgh, xxhzkieaah - xtqkfghuhr)
Phase 2
30
aioyyjvfop = xijvqwwrek aydwiichwu (vbjrzvgbet, vkxzltfhzq - yhpmdewfan)
-
15 May 2014
aioyyjvfop = ostzdvjanb aydwiichwu (vbjrzvgbet, wpgthxhjxn - bzkivfzfba)
Phase 2
92
qtevdysceb(grdmruewuy) = zzapwxstqu zudwlfttkb (rhziqoxefy )
Positive
01 Jan 2009
Vehicle-placebo
qtevdysceb(grdmruewuy) = worntfjgnj zudwlfttkb (rhziqoxefy )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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