Last update 21 Nov 2024

TT-00434

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
FGFR1 x FGFR2 x FGFR3
Mechanism
FGFR1 antagonists(Fibroblast growth factor receptor 1 antagonists), FGFR2 antagonists(Fibroblast growth factor receptor 2 antagonists), FGFR3 antagonists(Fibroblast growth factor receptor 3 antagonists)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Advanced Malignant Solid NeoplasmStomach Cancer
Inactive Indication-
Originator Organization
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.Startup
Active Organization
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.Startup
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with TT-00434
NCT04830501 / CompletedPhase 1
A Phase I Study of the Safety, Tolerability, Pharmacokinetics Profile, and Preliminary Efficacy of TT-00434 in Patients With Advanced Solid Tumors
100 Clinical Results associated with TT-00434
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100 Translational Medicine associated with TT-00434
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100 Patents (Medical) associated with TT-00434
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100 Deals associated with TT-00434
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
TW
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.Startup
12 Jul 2021
Stomach CancerPhase 1
US
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.Startup
-
Stomach CancerPhase 1
CN
TransThera Sciences (Nanjing), Inc.TransThera Sciences (Nanjing), Inc.Startup
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT04830501 (ESMO_ASIA2023)
ManualManual
Phase 1
Advanced Malignant Solid Neoplasm
11
(nocgfrswaj) = lvdjfyvcuc cwpbxxqggo (dzllpqmrmi )
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Positive
02 Dec 2023
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Approval

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Regulation

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