Last update 21 Nov 2024

Dexamethasone/Levofloxacin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
levofloxacin-dexamethasone, 左氧氟沙星地塞米松
Mechanism
Bacterial DNA gyrase inhibitors, GR agonists(Glucocorticoid receptor agonists), Top II modulators(Topoisomerase II modulators)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
DE (28 May 2020),
Regulation-
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Structure

Molecular FormulaC18H22FN3O5
InChIKeyQEHPHWRZQAZOTI-PPHPATTJSA-N
CAS Registry138199-71-0

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Cataract
CA
12 Dec 2023
Eye Infections, Bacterial
CA
12 Dec 2023
Ocular inflammation
IL
-
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ocular inflammationNDA/BLA
CN
10 Nov 2022
Ocular inflammationNDA/BLA
CN
10 Nov 2022
Ocular inflammationNDA/BLA
CN
10 Nov 2022
Eye InfectionsPhase 2--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
808
(Levofloxacin + Dexamethasone Followed by Dexamethasone)
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-
18 Aug 2020
(Tobramycin + Dexamethasone)
ohkfosfdsx(ltrrpfgsko) = adryqxbhhn akeklmpedp (vvteualmsv, ioeyeeymjp - szqdvtiqvi)
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Regulation

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