Request Demo
Last update 17 Sep 2026
HSK46575
Last update 17 Sep 2026
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms HSK46575 |
Target |
Action inhibitors |
Mechanism CYP11A1 inhibitors(Cytochrome P450 11A1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Login to view timeline
Related
2
Clinical Trials associated with HSK46575CTR20260988
评价HSK46575片联合抗肿瘤治疗在转移性去势抵抗性前列腺癌（mCRPC）患者中的安全性及有效性的Ib/II 临床研究
[Translation] A Phase Ib/II clinical study evaluating the safety and efficacy of HSK46575 tablets in combination with antitumor therapy in patients with metastatic castration-resistant prostate cancer (mCRPC).
NCT07007910
A Phase I Clinical Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of HSK46575 Tablets in Patients With Metastatic Castration-Resistant Prostate Cancer
100 Clinical Results associated with HSK46575
Login to view more data
100 Translational Medicine associated with HSK46575
Login to view more data
100 Patents (Medical) associated with HSK46575
Login to view more data
100 Deals associated with HSK46575
Login to view more data
R&D Status
10 top R&D records. to view more data
Login
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Metastatic castration-resistant prostate cancer | Phase 2 | China | 07 Apr 2026 | |
| Prostatic Cancer | IND Approval | China | 04 Dec 2024 |
Login to view more data
Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | Metastatic castration-resistant prostate cancer AR ligand-binding domain (AR-LBD) mutations | 27 | (AR-LBD mutant) | ttztvawfza(jpnsjleawd) = most of which were Grade 1-2. The most common TRAEs were alanine aminotransferase elevation (18.5%), sinus bradycardia (11.1%), and nausea (11.1%). ttwvejovcw (mbdjpxeyrd ) | Positive | 29 May 2026 | |
(AR-LBD mutant) |
Login to view more data
Translational Medicine
Boost your research with our translational medicine data.
login
or
Deal
Boost your decision using our deal data.
login
or
Core Patent
Boost your research with our Core Patent data.
login
or
Clinical Trial
Identify the latest clinical trials across global registries.
login
or
Approval
Accelerate your research with the latest regulatory approval information.
login
or
Regulation
Understand key drug designations in just a few clicks with Synapse.
login
or
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free