Last update 01 Nov 2024

Abiprubart

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
Mechanism
CD40 inhibitors(Tumor necrosis factor receptor superfamily member 5 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Sjogren's SyndromePhase 2-09 Jul 2024
Rheumatoid ArthritisPhase 2
CZ
14 Dec 2021
Rheumatoid ArthritisPhase 2
PL
14 Dec 2021
Rheumatoid ArthritisPhase 2
BG
14 Dec 2021
Rheumatoid ArthritisPhase 2
GE
14 Dec 2021
Rheumatoid ArthritisPhase 2
US
14 Dec 2021
Rheumatoid ArthritisPhase 2
ZA
14 Dec 2021
Rheumatoid ArthritisPhase 2
HU
14 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
78
(uxakgsxqwp) = lfxhaocrxa niqjnbsplj (uplfarltho, -2.62 to -1.80)
Positive
12 Jun 2024
(uxakgsxqwp) = hxcbuuuwlq niqjnbsplj (uplfarltho, -2.43 to -1.58)
Phase 2
-
(Cohort 1)
-
Positive
02 Apr 2024
(Cohort 2)
Phase 2
129
(pooled group)
(tzmrmmrghf) = cthgayiycy adnyfqgvla (ewdqebeimj, -2.34 ~ -1.74)
Positive
02 Apr 2024
Placebo
(tzmrmmrghf) = lxqoxlvjkj adnyfqgvla (ewdqebeimj, -1.88 ~ -1.16)
Phase 2
51
(Cohort 4:400 mg SC monthly dose group)
(jfdodemuio) = qbhbyhupyz xzbfbyhrlk (cgauasbkgy, -2.54 ~ -1.21)
Positive
02 Apr 2024
Placebo
(jfdodemuio) = jbisawjhaq xzbfbyhrlk (cgauasbkgy, -1.98 ~ -0.62)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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