Last update 21 Nov 2024

Bezetabart debotansine

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
Anti-CD74 antibody drug conjugates (Sutro Biopharma, Inc.)
+ [4]
Mechanism
CD74 inhibitors(HLA-DR antigens-associated invariant chain inhibitors), Tubulin inhibitors
Inactive Indication-
Originator Organization
Active Organization
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (US)
Login to view timeline

Structure

Molecular FormulaC35H48ClN3O10S
InChIKeyANZJBCHSOXCCRQ-FKUXLPTCSA-N
CAS Registry139504-50-0
View All Structures (2)
Boost your research with our ADC technology data.
Boost your research with our ADC technology data.

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
B-Cell LymphomaPhase 1
CN
16 Dec 2022
B-Cell LymphomaPhase 1
CN
16 Dec 2022
Diffuse Large B-Cell LymphomaPhase 1
CN
25 Nov 2022
Follicular LymphomaPhase 1
CN
25 Nov 2022
Mantle-Cell LymphomaPhase 1
CN
25 Nov 2022
Multiple MyelomaPhase 1
US
22 Feb 2018
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
18
(suxwuhgkhe) = chills, fatigue, nausea, anemia, headache, pyrexia, infusion reaction, decreased appetite, and abdominal pain occurring in ≥ 20% of patients. ywqzarjade (wupujimynb )
Positive
05 Nov 2020
Not Applicable
-
rfczxjhwps(hlaymchoyo) = Myelosuppression was observed at the highest dose, with no off-target toxicity yvcdqyaesv (yisfpkfydc )
Positive
07 Jun 2017
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free