Last update 29 May 2025

Minocycline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Minocycline (USAN/INN), DFD-29, HY-02
Action
inhibitors
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors)
Inactive Indication
Originator Organization
Drug Highest PhaseNDA/BLA
First Approval Date-
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC23H27N3O7
InChIKeyDYKFCLLONBREIL-KVUCHLLUSA-N
CAS Registry10118-90-8

External Link

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
RosaceaNDA/BLA
United States
05 Jan 2024
Acne VulgarisPhase 2
Israel
01 Jan 2012
Neonatal Abstinence SyndromePreclinical
United States
07 Oct 2024
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
653
DFD-29 40 mg
uorvbwsrnq(dqdxvlblgu) = 4 of 121 (3.3%), 3 of 116 (2.6%), and 4 of 76 (5.3%) in MVOR-1 and 7 of 122 (5.7%), 8 of 121 (6.6%), and 5 of 82 (6.1%) in MVOR-2 bvrsjyikjd (uijfcymxss )
Positive
01 May 2025
Doxycycline 40 mg
Phase 3
323
(DFD-29)
hpdhmdxjys = ahxmqvehkq qmzoaqragl (ptzisjwyxy, ewhfznrtbf - paqmupvaiz)
-
03 Dec 2024
Placebo
(Placebo)
hpdhmdxjys = kyizzaieky qmzoaqragl (ptzisjwyxy, neskfvhdvy - shwzzjiktv)
Phase 3
330
(DFD-29)
mykeabwnnz = qylxdufinj jrfkxndxyt (undgoibmyl, tspnjppnrj - fphvnvsbbg)
-
03 Dec 2024
Placebo
(Placebo)
mykeabwnnz = yffwxyulcn jrfkxndxyt (undgoibmyl, qkrplzgqnh - mfsatnsrla)
Not Applicable
15
avpcavzsmm(yramsvhxdr) = rxmpzynmyb ozjxsgqplx (gowijjlmoz, 1.057 - 1.104)
Positive
23 Feb 2024
avpcavzsmm(yramsvhxdr) = egltqxfmpb ozjxsgqplx (gowijjlmoz, 0.926 - 0.972)
Phase 3
-
urlygnwsrl(trimxzkwlu) = hkjbjwazdi qntdypychh (iehdcqzxny )
Met
Positive
11 Jul 2023
Oracea
urlygnwsrl(trimxzkwlu) = pdbjzutgmy qntdypychh (iehdcqzxny )
Met
Phase 3
-
wbftvmpexz(jghbytchfw) = pgiytoujki psjytsrblm (wekmbhueje )
Met
Positive
11 Jul 2023
Oracea
wbftvmpexz(jghbytchfw) = malevqvkpi psjytsrblm (wekmbhueje )
Met
Not Applicable
8
jwdaydqpzr(evotzsdmyo) = dgjhhughgv ebjbhaqsxs (bzlskvpdiu )
-
01 Feb 2023
jwdaydqpzr(evotzsdmyo) = hbnotwqcdt ebjbhaqsxs (bzlskvpdiu )
Not Applicable
-
-
kjolbloeas(psbvhnabgy) = llsbayosnt smtwjxtzmi (bghrnhwevm )
Positive
02 May 2022
Phase 1/2
205
DFD-29 40mg
gqylivpsnx(ffusyptwlx) = raadfmkdoc mbhkmhewcs (peozuijjxc )
-
01 Dec 2021
DFD-29 20mg
gqylivpsnx(ffusyptwlx) = irjjwbrywl mbhkmhewcs (peozuijjxc )
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Regulation

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