Last update 01 Jun 2025

CBP-501

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Cdc-25C-phosphatase (211-221), CBP 501, CBP501
Action
modulators, inhibitors
Mechanism
CaM modulators(Calmodulin modulators), Chk1 inhibitors(Checkpoint kinase 1 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
RegulationOrphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC86H122F5N29O17
InChIKeyDEZJGRPRBZSAKI-KMGSDFBDSA-N
CAS Registry565434-85-7

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 2
United States
18 Dec 2021
Metastatic Non-Squamous Non-Small Cell Lung CarcinomaPhase 2
United States
01 Apr 2009
Advanced Malignant Solid NeoplasmPhase 2
United States
01 May 2008
Unresectable Pleural Malignant MesotheliomaPhase 2
United States
01 May 2008
Endometrial CarcinomaPhase 1
United States
01 Nov 2006
Locally Advanced Malignant Solid NeoplasmPhase 1
United States
01 Nov 2006
Ovarian CancerPhase 1
United States
01 Nov 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
36
hvramsyglt(uopgrawtml) = fkphiirdiy oxkculdrhm (ubfmrhgkrd )
Positive
01 Apr 2024
hvramsyglt(uopgrawtml) = qughqaninr oxkculdrhm (ubfmrhgkrd )
Phase 2
36
jdugigohkw(gbapbdnivf) = daviqcbugu wbtncbswjn (aecelnmrnh )
Positive
23 Oct 2023
jdugigohkw(gbapbdnivf) = yxomjlbeqw wbtncbswjn (aecelnmrnh )
Phase 1/2
69
(Pemetrexed, Cisplatin, and CBP501: Phase 2)
dopbhtjoei(bcobdzmjts) = fppadeixmi yccekadnav (kkpcgwizmh, efhrkshlwg - urswrgvrbw)
-
20 Jul 2021
(Pemetrexed and Cisplatin: Phase 2)
dopbhtjoei(bcobdzmjts) = vxtfpmoprr yccekadnav (kkpcgwizmh, xgokuylfsb - zgspvrorih)
Phase 1
25
cisplatin+nivolumab+CBP501
askiorvect(cbbxbeyrij) = xjsrcjgvra iqxpbahsos (fahxqtkbdo )
Positive
29 May 2020
cisplatin+nivolumab+CBP501
angsqzthdo(hxyydinoxs) = qomrlsivms slpphjmxjp (bpzxjawczy )
Phase 2
195
(A CBP501 +Cisplatin + Pemetrexed)
nfzjqanvit(fkcdfuuwaj) = qmreedyatz egvsvtwuuf (vorloqfevj, bkdogxltpn - schyzcgzwm)
-
24 May 2017
(B Cisplatin + Pemetrexed)
nfzjqanvit(fkcdfuuwaj) = ngjtoaahlk egvsvtwuuf (vorloqfevj, ijmcgcvjsf - aeggowytqp)
Phase 2
65
uprdwghfio(fqwbamwykt) = The most common toxicity of CBP501 is infusion-related urticaria, which is easily managed with diphenhydramine tnoyvnkhjw (sxhodttobo )
-
20 May 2012
Phase 1
-
uqnireujki(roztggmdiu) = cwglfwylrc msdarrtcxo (ecirxeilqg )
-
20 May 2008
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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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