Last update 17 Dec 2024
Canlitinib
Last update 17 Dec 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms KC 1036, KC-1036 |
Target |
Mechanism AXL inhibitors(AXL receptor tyrosine kinase inhibitors), FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Structure
Molecular FormulaC33H31F2N3O7 |
InChIKeyPCKYITPVOLEZKL-UHFFFAOYSA-N |
CAS Registry2222730-78-9 |
Related
12
Clinical Trials associated with CanlitinibA Phase II Study to Evaluate the Safety and Efficacy of KC1036 in Adolescents Aged 12 and Above With Advanced Ewing Sarcoma
A Randomized, Controlled, Open-label, Multicenter Phase III Study to Evaluate the Efficacy and Safety of KC1036 Versus Investigator's Choice of Chemotherapy as Third-line Therapy in Patients With Advanced Esophageal Squamous Cell Carcinoma
评估KC1036对比研究者选择的化疗治疗晚期复发或转移性食管鳞癌受试者的随机、对照、开放、多中心III期临床研究
[Translation] A randomized, controlled, open-label, multicenter phase III clinical study evaluating KC1036 versus investigator-selected chemotherapy in patients with advanced recurrent or metastatic esophageal squamous cell carcinoma
100 Clinical Results associated with Canlitinib
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100 Translational Medicine associated with Canlitinib
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100 Patents (Medical) associated with Canlitinib
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100 Deals associated with Canlitinib
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Esophageal Squamous Cell Carcinoma | Phase 3 | CN | 26 Jan 2024 | |
| Ewing Sarcoma | Phase 2 | CN | 05 Aug 2024 | |
| thymic carcinoma | Phase 2 | CN | 22 Feb 2023 | |
| Metastatic thymic carcinoma | Phase 2 | CN | 07 Feb 2023 | |
| Recurrent Thymic Carcinoma | Phase 2 | CN | 07 Feb 2023 | |
| Metastatic Solid Tumor | Phase 2 | CN | 17 May 2022 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | CN | 28 Aug 2020 | |
| Advanced Lung Adenocarcinoma | IND Approval | CN | 11 Jan 2023 | |
| Hematologic Neoplasms | IND Application | CN | 20 Nov 2019 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
NCT05260385 (ASCO2023) Manual  | Phase 2 | 58 | dqyqxjobvc(mukwxgfzoo) = inqkndauhj iiyolrtuch (pvuudglhcf, 12.6 - 51.1) View more | Positive | 31 May 2023 | ||
Phase 1 | 41 | lvbkmqotuu(hwkcydxhvp) = 60 mg QD jtrgthqmun (hfirqgehkw ) | Positive | 26 May 2023 | |||
Phase 1 | - | evdqssqrgd(qnlebyxlgx) = Diarrhea (10.8%) oljzscseeo (amdhnvvgpr ) | Positive | 09 Jun 2022 |
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