Last update 08 Oct 2026

RAY-1225

Overview

Basic Info

Drug Type
Stapled peptide
Synonyms
Bilpatide, RAY 002, RAY 1225
+ [3]
Target
GIPR x GLP-1R
Action
agonists
Mechanism
GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Therapeutic Areas
Digestive System DisordersEndocrinology and Metabolic DiseaseNervous System Diseases+ [2]
Active Indication
Diabetes Mellitus, Type 2ObesityMetabolic Dysfunction Associated Steatohepatitis+ [1]
Inactive Indication
Hepatic InsufficiencyLiver Injury
Originator Organization
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
Active Organization
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
Inactive Organization-
License Organization
Qilu Pharmaceutical Group Co. Ltd.Qilu Pharmaceutical Group Co. Ltd.Guangdong Zhongsheng Pharmaceutical Co., Ltd.Guangdong Zhongsheng Pharmaceutical Co., Ltd.RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Related

13
Clinical Trials associated with RAY-1225
NCT07827027
/ Not yet recruitingPhase 1
Evaluation of the Bioequivalence of RAY1225 Injection in Healthy Participants in a Single-center, Randomized, Open-label, Parallel Study
NCT07460284
/ Not yet recruitingPhase 1
A Mass Balance Study of 14C-RAY1225 Injection in Healthy Chinese Participants
NCT07139535
/ Not yet recruitingPhase 3
A Randomized, Double-blind, Placebo-Controlled Trial Comparing the Efficacy and Safety of RAY1225 Versus Placebo in Patients With Type 2 Diabetes, Inadequately Controlled With Diet and Exercise Alone
100 Clinical Results associated with RAY-1225
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100 Translational Medicine associated with RAY-1225
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100 Patents (Medical) associated with RAY-1225
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100 Deals associated with RAY-1225
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 3
China
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
22 Aug 2025
ObesityPhase 3
China
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
15 Jun 2025
Metabolic Dysfunction Associated SteatohepatitisPhase 3
China
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
-
Hepatic InsufficiencyPhase 1
China
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
26 Aug 2024
Liver InjuryPhase 1
China
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
26 Aug 2024
Sleep Apnea, ObstructiveIND Approval
China
RAYNOVENT Co., Ltd.RAYNOVENT Co., Ltd.
23 Jan 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
REBUILDING-1 (ADA 12025 | ADA 22025 | NEWS)
ManualManual
Phase 2
Overweight | Obesity
132
atkoijqqrw(wfjiftxfdo) = uutpumzsja ztbtcfgdqp (juxtjuegdh, -11.63 to -8.49)
Positive
20 Jun 2025
atkoijqqrw(wfjiftxfdo) = ibxkqzifqa ztbtcfgdqp (juxtjuegdh, -14.51 to -11.43)
SHINING-1 (NEWS)
ManualManual
Phase 2
Diabetes Mellitus, Type 2
-
dsftwevyzt(ezpdwcvmaw) = blholxczse pqxnrnljll (uxnbwmgkyp )
Met
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Positive
31 Dec 2024
dsftwevyzt(ezpdwcvmaw) = poyhgultgs pqxnrnljll (uxnbwmgkyp )
Met
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REBUILDING-1 (NEWS)
ManualManual
Phase 2
Overweight | Obesity
122
RAY1225注射液 3mg
gmotpzpnxq(yuytceztck) = dmgoctasde ibvpplcvth (jonlsodplw )
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Positive
21 Nov 2024
RAY1225注射液 6mg
gmotpzpnxq(yuytceztck) = djsgutfhzx ibvpplcvth (jonlsodplw )
View more
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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