ES-009

SHANGHAI & SUZHOU, China & GERMANTOWN, Md.--(BUSINESS WIRE)-- Elpiscience Biopharma, Inc. (“Elpiscience”), a clinical-stage biopharmaceutical company dedicated to discovering and developing next-generation cancer immunotherapies, today announced that it will present the latest progress of its innovative molecules and powerful antibody generation platforms at the Biotech Showcase™ conference during J.P. Morgan Week 2023 in San Francisco in January. Elpiscience’s Co-Founder and CEO Darren Ji will also be sharing his perspective on the BioPharma Business in the Asia Pacific Region: Huge Markets, Great Opportunities panel at the conference. “We are excited to bring to the world our novel immunotherapies, including our first-in-class anti-CD39/TGF-β bispecific antibody ES014 potentially for PD-(L)1 resistant patient population, a highly differentiated anti-LILRB2 antibody ES009, and a pan-acting anti-SIPRα antibody ES004. We look forward to collaborating with pharmaceutical partners to advance our innovative drug candidates to benefit cancer patients worldwide,” said Darren Ji, Co-Founder, and CEO of Elpiscience. Event Schedules: Elpiscience’s presentation Darren Ji, Co-Founder and CEO of Elpiscience Date and Time: 9 January 2023, 14:30 – 14:45 PST Location: Hilton Union Square, Franciscan C (Ballroom Level), San Francisco CA Panel: BioPharma Business in the Asia Pacific Region: Huge Markets, Great Opportunities Darren Ji, Co-Founder and CEO of Elpiscience Date and Time: 10 January 2023, 9:00 – 10:00 PST Location: Hilton Union Square, Imperial Ballroom, San Francisco CA Elpiscience’s team is participating in partnering system and welcomes the opportunity to meet with potential partners. For meeting appointments, registered attendees can send a request through Biotech Showcase Partnering Platform, and or by contacting Elpiscience directly at BD@elpiscience.com. About Elpiscience Elpiscience is a clinical-stage biopharmaceutical company focused on developing next-generation immunotherapy to benefit cancer patients worldwide. The Company has a robust pipeline of globally innovative cancer immunotherapies covering a wide range of oncology targets and multiple proprietary technologies to enable discovery including its Bispecific Macrophage Engager (BiME®) antibody platform for solid tumors, human antibody Fab library ElpiSource™ and H-L interchain disulfide bond engineering BsAb platform Acebody™. Founded and managed by a team of biotechnology industry leaders and scientists, Elpiscience is supported by a world-class Scientific Advisory Board and high-quality investors including Lilly Asia Ventures, GL Ventures, Hyfinity Investments, Greater Bay Area Homeland Development Fund, CDH, DYEE Capital and Cormorant Asset Management. For more information, please visit .

SHANGHAI & SUZHOU, China & GERMANTOWN, Md.--(BUSINESS WIRE)-- Elpiscience Biopharma, Inc. (“Elpiscience”), a clinical-stage biopharmaceutical company focused on developing next-generation immunotherapies to benefit cancer patients worldwide, today announced it will have five poster presentations at the SITC 2022 Annual Meeting being held in Boston, Massachusetts from November 8-12. The posters will highlight studies on five innovative molecules including anti-SIRPα monoclonal antibody ES004, anti-LAG3 monoclonal antibody ES005, anti-LILRB2 monoclonal antibody ES009, anti-SIGLEC15 antibody ES012, and PD-L1/SIRPα bispecific macrophage engager ES019. Poster presentations: 1. Title: Treatment of anti-SIRPα in combination with anti-TAA exerts superior anti-tumor activity Abstract No.: 793 Date and time: 11/10/2022, 9:00 am - 9:00 pm (EST) 2. Title: Dual targeting of innate and adaptive immune checkpoints with a PD-L1/SIRPα bispecific macrophage engager to promote anti-tumor activity Abstract No.: 1211 Date and time: 11/10/2022, 9:00 am - 9:00 pm (EST) 3. Title: SIGLEC15 induces monocyte apoptosis and an SIGLEC15 antibody ES012 reverses myeloid cells driven immunosuppression Abstract No.: 1401 Date and time: 11/10/2022, 9:00 am - 9:00 pm (EST) 4. Title: ES005, a high affinity anti-LAG3 monoclonal antibody, inhibits the interactions between LAG3 and multiple ligands and enhances anti-tumor activity of T cells in preclinical models Abstract No.: 426 Date and time: 11/11/2022, 9:00 am - 9:00 pm (EST) 5. Title: ES009, a LILRB2-specific blocking antibody, reprograms myeloid cells into pro-inflammation phenotype and potentiates T cell activation Abstract No.: 1062 Date and time: 11/11/2022, 9:00 am - 9:00 pm (EST) About Elpiscience: Elpiscience is a clinical-stage biopharmaceutical company focused on developing next-generation immunotherapy to benefit cancer patients worldwide. The Company has a robust pipeline of globally innovative cancer immunotherapies covering wide range of oncology targets and multiple proprietary technologies to enable discovery including its Bispecific Macrophage Engager (BiME®) antibody platform for solid tumors. Founded and managed by a team of biotechnology industry leaders and scientists, Elpiscience is supported by a world-class Scientific Advisory Board and high-quality investors including, Lilly Asia Ventures, GL Ventures, Hyfinity Investments, Greater Bay Area Homeland Development Fund, CDH, DYEE Capital and Cormorant Asset Management. To learn more, visit elpiscience.com and follow us on LinkedIn.