Drug Type Small molecule drug |
Synonyms Darinaparsin (JAN/USAN), DMAs(III)G, SGLU + [11] |
Target |
Mechanism Reactive oxygen species stimulants, Apoptosis stimulants, Cell division inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (20 Jun 2022), |
RegulationOrphan Drug (US), Orphan Drug (EU) |
Molecular FormulaC12H22AsN3O6S |
InChIKeyJGDXFQORBMPJGR-YUMQZZPRSA-N |
CAS Registry69819-86-9 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Peripheral T-Cell Lymphoma | JP | 20 Jun 2022 | |
Peripheral T-Cell Lymphoma | JP | 20 Jun 2022 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Hepatocellular Carcinoma | Phase 2 | US | 01 Jan 2007 | |
Bone Marrow Neoplasms | Phase 2 | US | 01 Dec 2006 | |
Multiple Myeloma | Phase 2 | CA | 01 Jan 2006 | |
Hepatocellular Carcinoma | Phase 2 | - | - | |
Hepatocellular Carcinoma | Phase 2 | - | - | |
Lymphoma | Phase 1 | - | 01 Jun 2010 | |
Advanced cancer | Phase 1 | US | 01 Aug 2007 | |
Advanced Malignant Solid Neoplasm | Phase 1 | US | 01 Aug 2007 | |
acute leukemia | Phase 1 | US | 01 May 2005 | |
Myelodysplastic Syndromes | Phase 1 | US | 01 May 2005 |
Phase 2 | 65 | yosazymtob(ojzmlpqvev) = pvepljejvo chwydwbavk (gpczzrygrz, 11.2 - 29.9) | Positive | 20 Jan 2023 | |||
Phase 1 | 23 | qoyyecdols(qlzxbmuwfu) = lymphopenia (9%), neutropenia (9%) and thrombocytopenia (9%) mjyvjvfuvm (gvwwrmpfqm ) | Positive | 08 Feb 2021 | |||
NCT02653976 (Biospace) Manual | Phase 2 | - | flsodagbrv(eshlanmeqn) = reach feazljxcyr (fsloiorfzs ) View more | Positive | 15 Jun 2020 | ||
Phase 1 | 47 | twhyfzmnsg(adholwfzww) = vkgbnzufas uvljinryyx (xpdohohhgl ) View more | - | 15 Jul 2009 | |||
Phase 2 | 15 | zgvzuieqji(tbsrmjcypu) = clnuyiului kvldyeanhn (hroopnxfni, 93 - 227) View more | Negative | 20 May 2009 | |||
Phase 1 | 34 | wrjglksmnx(ksvzmknukd) = transient confusion, and ataxia wfpohslsvq (ttphenmepk ) View more | - | 20 Jun 2007 | |||
Phase 1/2 | 19 | jthfuanbrn(mvwadevdhe) = transient confusion /ataxia smxuqyrzlj (snebvyzkvu ) | - | 20 Jun 2007 | |||
Phase 1 | 8 | ssnvjycjpu(rllskkyeqe) = pzmbgvhrzo hcfsynzolm (qzcthhsjjk ) View more | - | 20 Jun 2006 |